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By Targets:	Isotope-Labeled Compounds (1) Keap1-Nrf2 (2) Liposome (2) Radionuclide-Drug Conjugates (RDCs) (1) Reference Standards (1) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (4)
Oligonucleotides:	Cationic Lipids (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Inhibitory Antibodies

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112675

4-Octyl itaconate 85+ Cited Publications 4-OI	Keap1-Nrf2	Inflammation/Immunology
4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 .

HY-151507

306Oi10 1 Publications Verification	Liposome	Others
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .

HY-167012

306Oi9-cis2	Liposome	Others
306Oi9-cis2 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 306Oi9-cis2 can be used in the preparation of liposomes .

HY-P992430

OI-3	Transmembrane Glycoprotein Radionuclide-Drug Conjugates (RDCs)	Inflammation/Immunology Cancer
OI-3 is a monoclonal antibody targeting CD146 (MCAM). OI-3 specifically binds to CD146 on the surface of human mesothelioma cells and undergoes endocytosis; both chimeric (chOI-3) and murine (mOI-3) variants possess this activity. When conjugated with ²¹²Pb to form ²¹²Pb-TCMC-OI-3, OI-3 acts as a cytotoxic agent that delivers α-emitting radionuclides to induce targeted cytotoxicity. OI-3 can be used in research related to malignant peritoneal mesothelioma .

HY-112675R

4-Octyl itaconate (Standard) 4-OI (Standard)	Reference Standards Keap1-Nrf2	Inflammation/Immunology
4-Octyl itaconate (Standard) is the analytical standard of 4-Octyl itaconate. This product is intended for research and analytical applications. 4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1[1].

HY-112675S

4-Octyl itaconate-13C5-1 4-OI-¹³C₅-1	Isotope-Labeled Compounds	Others
4-Octyl itaconate- ¹³C₅-1 is ¹³C-labeled 4-Octyl itaconate (HY-112675). Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

Cat. No.	Product Name	Type

HY-151507

306Oi10 1 Publications Verification	Biochemical Assay Reagents
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .

306Oi10

1 Publications Verification

Biochemical Assay Reagents

306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .

HY-167012

306Oi9-cis2	Biochemical Assay Reagents
306Oi9-cis2 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 306Oi9-cis2 can be used in the preparation of liposomes .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99398

Setrusumab BPS 804	Inhibitory Antibodies	Inflammation/Immunology Cancer
Setrusumab (BPS 804) is a fully human monoclonal antibody targets sclerostin. Setrusumab efftively improves bone strength. Setrusumab can be used for the resesrch of Osteogenesis Imperfecta (OI) and cancer .

HY-P992430

OI-3	Transmembrane Glycoprotein Radionuclide-Drug Conjugates (RDCs)	Inflammation/Immunology Cancer
OI-3 is a monoclonal antibody targeting CD146 (MCAM). OI-3 specifically binds to CD146 on the surface of human mesothelioma cells and undergoes endocytosis; both chimeric (chOI-3) and murine (mOI-3) variants possess this activity. When conjugated with ²¹²Pb to form ²¹²Pb-TCMC-OI-3, OI-3 acts as a cytotoxic agent that delivers α-emitting radionuclides to induce targeted cytotoxicity. OI-3 can be used in research related to malignant peritoneal mesothelioma .

4-Octyl itaconate-13C5-1
4-Octyl itaconate- ¹³C₅-1 is ¹³C-labeled 4-Octyl itaconate (HY-112675). Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

Host:	Mouse (6) Rabbit (2)
Reactivity:	Human (8) Rat (6) Mouse (6) Monkey (2) Rabbit (1)
Application:	IHC-P (2) ICC/IF (6) WB (4) FC (4) ELISA (2)
Isotype:	IgG (2) IgG1 (6)
Conjugation:	Non-conjugated (8)
Clonality:	Polyclonal (1) Monoclonal (3) Monoclonal Antibody (1) Recombinant (1)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88368

	LEPRE1 Antibody (YA8052) GROS1; LEPRE1; OI8	ICC/IF, FC	Human
	LEPRE1 Antibody (YA8052) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LEPRE1.

HY-P88110

	BMP1 Antibody (YA7794) OI13; PCOLC; PCP; PCP2; TLD	ICC/IF	Human, Mouse, Rat
	BMP1 Antibody (YA7794) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to BMP1.

HY-P88368A

	LEPRE1 Antibody (YA8052)(PBS only) GROS1; LEPRE1; OI8	ICC/IF, FC	Human
	LEPRE1 Antibody (YA8052) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LEPRE1.

HY-P88110A

	BMP1 Antibody (YA7794)(PBS only) OI13; PCOLC; PCP; PCP2; TLD	ICC/IF	Human, Mouse, Rat
	BMP1 Antibody (YA7794) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to BMP1.

HY-P83998

	Collagen I alpha 2 Antibody (YA3695) OI4; EDSCV; EDSARTH2	WB, ICC/IF, FC, ELISA	Human, Mouse, Rat, Monkey
	Collagen I alpha 2 Antibody (YA3695) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Collagen I alpha 2.

HY-P83998A

	Collagen I alpha 2 Antibody (YA3695)(PBS only) OI4; EDSCV; EDSARTH2	WB, ICC/IF, FC, ELISA	Human, Mouse, Rat, Monkey
	Collagen I alpha 2 Antibody (YA3695) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Collagen I alpha 2.

HY-P82863

	Hsp47 Antibody (YA2608) CBP1; CBP2; OI10; gp46; AsTP3; HSP47; PIG14; PPROM; RA-A47; SERPINH2	WB, IHC-P	Human, Mouse, Rat
	Hsp47 Antibody (YA2608) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp47.

HY-P81227

	Collagen I Antibody 3 Publications Verification Collagen type I; Alpha 1 type I collagen; Alpha 2 type I collagen; COL1A1; COL1A2; Collagen I alpha 1 polypeptide; Collagen I alpha 2 polypeptide; Collagen Of Skin Tendon And Bone; Collagen Type 1; Collagen type I alpha 1; Collagen type I alpha 2; OI4; Osteogenesis Imperfecta Type IV; Pro alpha 1(I) collagen; Type I procollagen; CO1A1_HUMAN.	WB, IHC-P	Human, Mouse, Rat, Rabbit
	Collagen I Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Collagen I.

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Cat. No.	Product Name		Classification

HY-151507

306Oi10 1 Publications Verification		Cationic Lipids
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .

HY-167012

306Oi9-cis2		Cationic Lipids
306Oi9-cis2 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 306Oi9-cis2 can be used in the preparation of liposomes .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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