7 Results for "

Paeoniflorin

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Paeoniflorin" in MCE Product Catalog:

41
Paeoniflorin
Paeoniflorin
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41 Cited Publications
Referencia número: HY-N0293
No. CAS: 23180-57-6
Synonyms: Peoniflorin
Category:  

Other Monoterpenes Paeonia lactiflora Pall. Terpenoids Plants Paeoniaceae

Target:  

HSP

Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .
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Galloylpaeoniflorin
Galloylpaeoniflorin
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Referencia número: HY-N5048
No. CAS: 122965-41-7
Synonyms: 6'-O-Galloyl Paeoniflorin
Category:  

Paeonia lactiflora Pall. Other Diseases Phenols Polyphenols Plants Paeoniaceae Disease Research Fields

Target:  

NF-κB ERK JNK Nuclear Factor of activated T Cells (NFAT) Keap1-Nrf2 PI3K Akt Reactive Oxygen Species (ROS) Apoptosis DNA/RNA Synthesis

Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) is an orally active galloylated derivative of Paeoniflorin (HY-N0293) found in peony roots with various anti-inflammatory and antioxidant activities. Galloylpaeoniflorin suppresses RANKL-induced activation of ERK, JNK, c-Fos, c-Jun, and NFATc1, and reduces osteoclast-specific gene expression. Galloylpaeoniflorin activates Nrf2 and PI3K/Akt pathways, inhibits NF-κB activation, and scavenges ROS to reduce oxidative DNA, lipid, and protein damage. Galloylpaeoniflorin attenuates neuroinflammation, inhibits apoptosis, reduces Helicobacter pylori-induced gastric mucosa injury and UVB-induced cell damage. Galloylpaeoniflorin can be used for the research of osteoporosis, gastritis, ischemic stroke and skin diseases .
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Paeoniflorin (Standard)
Paeoniflorin (Standard)
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Referencia número: HY-N0293R
No. CAS: 23180-57-6
Synonyms: Peoniflorin (Standard)
Category:  

Other Monoterpenes Paeonia lactiflora Pall. Terpenoids Plants Paeoniaceae

Target:  

Reference Standards HSP

Paeoniflorin (Standard) is the analytical standard of Paeoniflorin. This product is intended for research and analytical applications. Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .
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Paeoniflorgenin
Paeoniflorgenin
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Referencia número: HY-N7686
No. CAS: 697300-41-7
Category:  

Natural Products Paeonia lactiflora Pall. Other Diseases Plants Paeoniaceae Disease Research Fields

Target:  

Drug Metabolite

Paeoniflorgenin is a deglucosylated metabolite of Paeoniflorin .
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Paeoniflorin sulfite
Paeoniflorin sulfite
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Referencia número: HY-N7639
No. CAS: 1146967-98-7
Category:  

Natural Products other families Other Diseases Plants Disease Research Fields

Target:  

Others

Paeoniflorin, a main component of Paeoniae Radix Alba, could be transformed into Paeoniflorin sulfite during sulfur-fumigation of Paeoniae Radix Alba .
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Paeoniflorin-6′-O-benzene sulfonate
Paeoniflorin-6′-O-benzene sulfonate
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Referencia número: HY-168971
No. CAS: 1390658-79-3
Synonyms: CP-25
Target:  

IFNAR STAT TNF Receptor Interleukin Related CXCR JAK G Protein-coupled Receptor Kinase (GRK)

Áreas de investigación:  

Inflammation/Immunology

Paeoniflorin-6′-O-benzene sulfonate (CP-25) is the inhibitor for G protein-coupled receptor kinase 2 (GRK2) that inhibits the translocation of GRK2 to the cell membrane, inhibits JAK1/STAT3 signaling pathway. Paeoniflorin-6′-O-benzene sulfonate inhibits IL-17A/CXCL2-induced proliferation of HaCaT. Paeoniflorin-6′-O-benzene sulfonate reduces the levels of inflammatory factors and chemokines such as IL-17A, IL-17F, IFN-γ, TNF-α, IL-22, IL-23, CXCL2, CXCL3 and CXCL9, alleviates Imiquimod (HY-B0180)-induced psoriasis in mouse model .
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Mudanpioside E
Mudanpioside E
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Referencia número: HY-N18182
No. CAS: 172705-25-8
Category:  

Monophenols Paeonia lactiflora Pall. Phenols Plants Paeoniaceae

Target:  

Glycosidase

Mudanpioside E is an orally effective paeoniflorin-type monoterpene glycoside antiallergic agent, with an IC50 of 40.34 μM against IgE-mediated β-hexosaminidase release. Mudanpioside E reverses the inhibitory effect of the modified Xiaoqinglong Decoction extract (paeonia root component removed) on passive cutaneous anaphylaxis in mice. Mudanpioside E itself shows no activity against passive cutaneous anaphylaxis. Mudanpioside E can be used in research related to allergic diseases .
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