2. Search Result
Search Result
Results for "

RDX

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

6

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15991
    Tenapanor
    5+ Cited Publications

    AZD1722; RDX5791

    		 Na+/H+ Exchanger (NHE) Metabolic Disease
    Tenapanor (AZD1722) is a potent and orally active sodium/hydrogen exchanger isoform 3 (NHE3) inhibitor. Tenapanor reduces intestinal phosphate absorption predominantly through reduction of passive paracellular phosphate flux. Tenapanor has the potential for the research of hyperphosphatemia .
    Tenapanor
  • HY-15991A
    Tenapanor hydrochloride
    5+ Cited Publications

    AZD1722 hydrochloride; RDX5791 hydrochloride

    		 Na+/H+ Exchanger (NHE) Metabolic Disease
    Tenapanor (AZD1722) hydrochloride is a potent and orally active sodium/hydrogen exchanger isoform 3 (NHE3) inhibitor. Tenapanor hydrochloride reduces intestinal phosphate absorption predominantly through reduction of passive paracellular phosphate flux. Tenapanor hydrochloride has the potential for the research of hyperphosphatemia .
    Tenapanor hydrochloride
  • HY-13631J
    (1R,9R)-Exatecan mesylate

    (1R,9R)-DX8951f

    		 Drug Derivative Topoisomerase Apoptosis Cancer
    (1R,9R)-Exatecan mesylate ((1R,9R)-DX8951f) is a non-prodrug camptothecin derivative and a potent topoisomerase I inhibitor (IC50=0.975 μg/mL in mice and 0.82 μg/mL in humans). (1R,9R)-Exatecan mesylate blocks enzyme activity and induces apoptosis by stabilizing the enzyme-DNA cleavable complex. (1R,9R)-Exatecan mesylate not only effectively inhibits the proliferation of various malignant tumor cells and tumor growth, but also circumvents P-glycoprotein-mediated multidrug resistance. (1R,9R)-Exatecan mesylate is widely used in preclinical studies of multiple cancers including pancreatic cancer, lung cancer, breast cancer, and leukemia . The low-activity isomer of (1R,9R)-Exatecan mesylate is (1S,9R)-Exatecan mesylate (HY-13631I).
    (1R,9R)-Exatecan mesylate
  • HY-13631I
    (1S,9R)-Exatecan mesylate

    (1S,9R)-DX8951f

    		 Drug Derivative Topoisomerase Apoptosis Cancer
    (1S,9R)-Exatecan mesylate ((1S,9R)-DX8951f) is a non-prodrug camptothecin derivative and a topoisomerase I inhibitor (IC50=0.975 μg/mL in mice and 0.82 μg/mL in humans). (1S,9R)-Exatecan mesylate blocks enzyme activity and induces apoptosis by stabilizing the enzyme-DNA cleavable complex. (1S,9R)-Exatecan mesylate not only effectively inhibits the proliferation of various malignant tumor cells and tumor growth, but also circumvents P-glycoprotein-mediated multidrug resistance. (1S,9R)-Exatecan mesylate is widely used in preclinical studies of various cancers such as pancreatic cancer, lung cancer, breast cancer, and leukemia .
    The chiral isomer of (1S,9R)-Exatecan mesylate is (1R,9R)-Exatecan mesylate (HY-13631J).
    (1S,9R)-Exatecan mesylate
  • HY-P2800
    Diaphorase, Recombinant microorganisms

    		Endogenous Metabolite Others
    Diaphorase, Recombinant microorganisms can be obtained from anaerobic sludge organisms. Diaphorase catalyzes biotransformation of hexahydro-1,3, 5-trinitro-1,3, 5-triazine (RDX) by denitrification .
    Diaphorase, Recombinant microorganisms
  • HY-RS11806
    RDX Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    RDX Human Pre-designed siRNA Set A contains three designed siRNAs for RDX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    RDX Human Pre-designed siRNA Set A
    RDX Human Pre-designed siRNA Set A
  • HY-RS18121
    Rdx Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    Rdx Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rdx gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Rdx Mouse Pre-designed siRNA Set A
    Rdx Mouse Pre-designed siRNA Set A
  • HY-RS24595
    Rdx Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Rdx Rat Pre-designed siRNA Set A contains three designed siRNAs for Rdx gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Rdx Rat Pre-designed siRNA Set A
    Rdx Rat Pre-designed siRNA Set A

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: