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Results for "

SLC7A5

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

3

Antibodies

3

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-120139
    KMH-233
    1 Publications Verification

    		 Amino acid Transporter Cancer
    KMH-233, a potent, reversible and selective inhibitor of l-type amino acid transporter LAT1/SLC7A5, inhibits the uptake of LAT1 substrate, l-leucin (IC50=18 μM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 μM) .
    KMH-233
  • HY-RS13331
    SLC7A5 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SLC7A5 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC7A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SLC7A5 Human Pre-designed siRNA Set A
    SLC7A5 Human Pre-designed siRNA Set A
  • HY-133677
    Mono(2-ethyl-5-hydroxyhexyl) phthalate

    MEHHP

    		 Drug Metabolite Apoptosis Aryl Hydrocarbon Receptor Cancer
    Mono (2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) is a biomarker for human exposure to DEHP (HY-B1945). By activating the tryptophan-kynurenine-aryl hydrocarbon receptor (AhR) pathway, mono (2-ethyl-5-hydroxyhexyl) phthalate significantly increases the viability of primary uterine leiomyoma cells and reduces cell apoptosis. Mono (2-ethyl-5-hydroxyhexyl) phthalate correlates with decreased sperm DNA damage. Mono (2-ethyl-5-hydroxyhexyl) phthalate can be used in studies related to uterine leiomyoma .
    Mono(2-ethyl-5-hydroxyhexyl) phthalate
  • HY-158161
    SLC6A19-IN-1

    		Amino acid Transporter Metabolic Disease
    SLC6A19-IN-1 is a potent and highly selective inhibitor and transport corrector of human SLC6A19 (IC50=47 nM). Furthermore, at a concentration of 35 μM, SLC6A19-IN-1 exhibits no activity against SLC1A5, SLC7A5, or SLC6A8. SLC6A19-IN-1 is applicable to research on phenylketonuria (PKU) and hyperphenylalaninemia. SLC6A19-IN-1 is also suitable for studies related to various metabolic disorders, including tyrosinemia, maple syrup urine disease, urea cycle disorders, and hyperammonemia .
    SLC6A19-IN-1
  • HY-RS17279
    Slc7a5 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Slc7a5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc7a5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Slc7a5 Mouse Pre-designed siRNA Set A
    Slc7a5 Mouse Pre-designed siRNA Set A
  • HY-RS23734
    Slc7a5 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Slc7a5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc7a5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Slc7a5 Rat Pre-designed siRNA Set A
    Slc7a5 Rat Pre-designed siRNA Set A
  • HY-W267524
    H-Phe(3-CF3)-OH

    		Drug Derivative Cancer
    H-Phe (3-CF3)-OH is a phenylalanine derivative targeting the L-type amino acid transporter 1 (LAT1, SLC7A5) as its core target, and it belongs to LAT1 substrates. H-Phe (3-CF3)-OH can be used for prodrug scaffold development and research related to multiple solid tumors .
    H-Phe(3-CF3)-OH
  • HY-183513
    L-Ala-BPA

    		FAP Cancer
    L-Ala-BPA is a boron delivery agent. L-Ala-BPA is transported into tumor cells via PEPT1/2 and LAT-1 (SLC7A5) pathways and is rapidly cleaved systemically by endogenous proteases including FAP to yield L-BPA (HY-W087830). L-Ala-BPA shows antitumor activity and can be used for the research of Boron Neutron Capture Therapy (BNCT) .
    L-Ala-BPA
  • HY-W772441
    H-Phe(3-tBu)-OH hydrochloride

    		Amino Acid Derivatives Others
    H-Phe(3-tBu)-OH hydrochloride is an amino acid derivative commonly used in biochemical research and organic synthesis .
    H-Phe(3-tBu)-OH hydrochloride
  • HY-164401A
    QBS10072S dihydrochloride

    		EAAT DNA/RNA Synthesis DNA Alkylator/Crosslinker Cancer
    QBS10072S dihydrochloride is a LAT1-selective substrate with blood-brain barrier permeability that inhibits tumor growth. QBS10072S dihydrochloride enters LAT1-expressing tumor cells via LAT1-mediated active transport, induces interstrand DNA cross-linking and cell apoptosis, and reduces leptomeningeal dissemination. QBS10072S dihydrochloride can be used in studies related to glioblastoma multiforme, diffuse intrinsic pontine glioma, triple-negative breast cancer brain metastases, and aggressive T-cell lymphoma .
    QBS10072S dihydrochloride

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