2 Results for "

Terodiline

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Terodiline" in MCE Product Catalog:

Cat. No.: HY-16489
CAS No.: 15793-40-5
Research Areas:  

Metabolic Disease

Terodiline, an antispasmodic agent, blocks hERG current with the IC50 of 375 nM. Terodiline has both anticholinergic and calcium antagonist properties, and effectively reduces abnormal bladder contractions caused by detrusor instability. Terodiline can be used for the research of urinary incontinence .
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Cat. No.: HY-16489A
CAS No.: 7082-21-5
Target:  

mAChR Calcium Channel

Research Areas:  

Neurological Disease

Terodiline hydrochloride is an M1-selective muscarinic receptor (mAChR) antagonist with Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively. Terodiline hydrochloride also is a Ca 2+ blocker. Terodiline hydrochloride acts as a treatment for urinary frequency and urge incontinence .
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