Terodiline hydrochloride
Based on 1 Customer Validation
Terodiline hydrochloride is an M1-selective muscarinic receptor (mAChR) antagonist with Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively. Terodiline hydrochloride also is a Ca2+ blocker. Terodiline hydrochloride acts as a treatment for urinary frequency and urge incontinence.
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- Pureté : 99.5%
- CAS No.: 7082-21-5
- Formule: C20H28ClN
- Masse moléculaire:317.90
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Stockage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Fmale or male Hartley guinea pigs (200-600 g)[1]
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Dosage:80 mg/kg
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Administration:Administered S.C.
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Result:Yielded an ID50 of 24±6 mg/kg. Higher doses were Iethal.
Chemical Information
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CAS No. 7082-21-5
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Appearance Solid
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Masse moléculaire 317.90
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Formule C20H28ClN
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Color White to off-white
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SMILES
CC(NC(C)(C)C)CC(C1=CC=CC=C1)C2=CC=CC=C2.[H]Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
In Vitro:
DMSO : 40 mg/mL (125.83 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureté et documentation
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Fiche technique (274 KB)
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SDS (598 KB)
- English - EN (598 KB)
- Français - FR (598 KB)
- Deutsch - DE (598 KB)
- Norwegian - NO (598 KB)
- Español - ES (598 KB)
- Swedish - SV (598 KB)
- Italian - IT (598 KB)
- Korean - KR (598 KB)
- Portuguese - PT (598 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1456 mL | 15.7282 mL | 31.4564 mL | 78.6411 mL |
| 5 mM | 0.6291 mL | 3.1456 mL | 6.2913 mL | 15.7282 mL | |
| 10 mM | 0.3146 mL | 1.5728 mL | 3.1456 mL | 7.8641 mL | |
| 15 mM | 0.2097 mL | 1.0485 mL | 2.0971 mL | 5.2427 mL | |
| 20 mM | 0.1573 mL | 0.7864 mL | 1.5728 mL | 3.9321 mL | |
| 25 mM | 0.1258 mL | 0.6291 mL | 1.2583 mL | 3.1456 mL | |
| 30 mM | 0.1049 mL | 0.5243 mL | 1.0485 mL | 2.6214 mL | |
| 40 mM | 0.0786 mL | 0.3932 mL | 0.7864 mL | 1.9660 mL | |
| 50 mM | 0.0629 mL | 0.3146 mL | 0.6291 mL | 1.5728 mL | |
| 60 mM | 0.0524 mL | 0.2621 mL | 0.5243 mL | 1.3107 mL | |
| 80 mM | 0.0393 mL | 0.1966 mL | 0.3932 mL | 0.9830 mL | |
| 100 mM | 0.0315 mL | 0.1573 mL | 0.3146 mL | 0.7864 mL |
Terodiline hydrochloride Related Classifications
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