18 Results for "

Thiouracil

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "Thiouracil" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-100873
CAS No.: 1435467-38-1
Purity:  99.80%
Synonyms: PF-06281355
Research Areas:  

Cardiovascular Disease

PF-1355 is a selective 2-thiouracil mechanism-based MPO inhibitor, used for treatment of vasculitic diseases.
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-B0346
CAS No.: 51-52-5
Synonyms: 6-n-PropylThiouracil; 6-Propyl-2-Thiouracil; PTU
Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-B0503
CAS No.: 141-90-2
Synonyms: Thiouracil
Target:  

NO Synthase

Research Areas:  

Endocrinology Cancer

2-Thiouracil (Thiouracil) is a selective neuronal nitric oxide synthase (nNOS) inhibitor with a Ki value of 20 μM. 2-Thiouracil antagonizes BH4-induced nNOS dimerization. 2-Thiouracil is also an antithyroid compound and a highly specific melanoma detector. 2-Thiouracil stimulates the growth of pea and corn root segments .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-128425A
CAS No.: 13184-27-5
Purity:  ≥98.0%
Synonyms: L-Ureidosuccinic acid
N-Carbamoyl-L-aspartic acid (L-Ureidosuccinic acid) is an important pyrimidine metabolic precursor and intermediate metabolite. N-Carbamoyl-L-aspartic acid reverses the growth inhibition of Ura + strains induced by 2-thiouracil (with growth rate increasing linearly with its concentration), but fails to support the growth of uracil-requiring Ura - strains. N-Carbamoyl-L-aspartic acid inhibits the cell growth of *Saccharomyces cerevisiae* by suppressing the purine biosynthetic pathway at a pre-step of 5-aminoimidazole nucleotide synthesis. The growth inhibitory effect of N-Carbamoyl-L-aspartic acid on yeast can be alleviated by purines, and the sensitivity of strains is closely related to the activity level of dihydroorotase .
loading...
    loading...
Cat. No.: HY-W010417
CAS No.: 591-28-6
Research Areas:  

Others

4-Thiouracil is a thionucleobase with cytostatic properties. 4-Thiouracil can be used as biological photoprobes to detect RNA structures and nucleic acid-nucleic acid contacts. 4-Thiouracil can also act as a strong ultraviolet A (UVA) photosensitizer, providing a source of the reactive oxygen species of O2. 4-Thiouracil is promising for research of photocross linking, photodamage, as well as photodynamic therapy .
loading...
    loading...
Cat. No.: HY-W069177
CAS No.: 6336-50-1
Synonyms: 6-Benzyl-2-Thiouracil
Target:  

TSH Receptor

Research Areas:  

Others

Benzylthiouracil is an active pharmaceutical ingredient against hyperthyroidism .
loading...
    loading...
Cat. No.: HY-B0346R
CAS No.: 51-52-5
Synonyms: 6-n-PropylThiouracil (Standard); 6-Propyl-2-Thiouracil (Standard); PTU (Standard)
Propylthiouracil (Standard) is the analytical standard of Propylthiouracil. This product is intended for research and analytical applications. Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research .
loading...
    loading...
Cat. No.: HY-B0503S
CAS No.: 2923524-84-7
Synonyms: Thiouracil-13C,15N2
2-Thiouracil- 13C, 15N2 is the 13C, 15N labeled 2-Thiouracil. 2-Thiouracil (Thiouracil) is an antithyroid compound. 2-Thiouracil can function as a highly specific melanoma seeker. 2-Thiouracil is a selective inhibitor of neuronal nitric oxide synthase (nNOS) with a Ki of 20 μM.
loading...
    loading...
Cat. No.: HY-W052750
CAS No.: 23945-50-8
5-Carboxy-2-thiouracil is a compound with antitumor activity that can form complexes with metal ions, thereby exhibiting significant biological effects.
loading...
    loading...
Cat. No.: HY-W778297
CAS No.: 1346601-57-7
5,6-Diamino-4-thiouracil- 13C2 is the 13C-labeled 5,6-Diamino-4-thiouracil (HY-W740396).
loading...
    loading...
Cat. No.: HY-W012478S
6-Phenyl-2-thiouracil- 13C, 15N2 is the 13C, 15N labeled 6-Phenyl-2-thiouracil.
loading...
    loading...
Cat. No.: HY-152343
CAS No.: 2305416-17-3
Research Areas:  

Others

1-(β-D-Xylofuranosyl)-2-thiouracil is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
loading...
    loading...
Cat. No.: HY-B0346S
CAS No.: 1189423-94-6
Synonyms: 6-n-PropylThiouracil-d5; 6-Propyl-2-Thiouracil-d5; PTU-d5
Propylthiouracil-d5 is the deuterium labeled Propylthiouracil. Propylthiouracil (6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor.
loading...
    loading...
Cat. No.: HY-W766699
CAS No.: 1246816-15-8
Synonyms: 6-Amino-2-Thiouracil Monohydrate-13C
6-Amino-4-hydroxy-2-mercaptopyrimidine- 13C (6-Amino-2-thiouracil Monohydrate- 13C) is the 13C-labeled 6-Amino-4-hydroxy-2-mercaptopyrimidine (HY-75601).
loading...
    loading...
Cat. No.: HY-W777759
CAS No.: 1246814-68-5
Synonyms: 4-Amino-6-hydroxy-2-mercapto-5-nitrosopyrimidine-13C,15N
6-Amino-5-nitroso-2-thiouracil- 13C, 15N (4-Amino-6-hydroxy-2-mercapto-5-nitrosopyrimidine- 13C, 15N) is the 13C- and 15N-labeled 6-Amino-5-nitroso-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (HY-75602).
loading...
    loading...
Cat. No.: HY-100873R
CAS No.: 1435467-38-1
Synonyms: PF-06281355 (Standard)
PF-1355 (Standard) is the analytical standard of PF-1355 (HY-100873). This product is intended for research and analytical applications. PF-1355 is a selective 2-thiouracil mechanism-based MPO inhibitor, used for treatment of vasculitic diseases.
loading...
    loading...
Cat. No.: HY-P11685
CAS No.: 2245800-85-3
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Fmoc-PNA-thioU(PMB)-OH is a nucleobase-modified peptide nucleic acid (PNA) monomer used in solid-phase synthesis. Fmoc-PNA-thioU(PMB)-OH features a thiouracil base protected with a p-methoxybenzyl (PMB) group on an Fmoc-protected backbone, designed for incorporating modified PNA bases into oligonucleotides to study binding properties.
loading...
    loading...
Cat. No.: HY-P11680
CAS No.: 253438-99-2
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

BOC-PNA-thioU(PMB)-OH is a peptide nucleic acid (PNA) monomer characterized by a PMB protecting group on its thiouracil, which enhances its binding affinity to adenine. BOC-PNA-thioU(PMB)-OH exhibits excellent resistance to enzymatic degradation and strong hybridization properties, making it valuable for applications in gene diagnosis, antisense therapy, and other molecular biology fields requiring higher binding strength and greater functionalization.
loading...
    loading...
  • 1