253438-99-2
Chemical Structure
Boc-PNA-thioU(PMB)-OH
- CAS No.: 253438-99-2
- Formula:C23H30N4O7S
- Molecular Weight:506.57
InChIKey: HDKCTBBIWSKCEV-UHFFFAOYSA-N
SMILES: O=C1N=C(N(CC(N(CCNC(OC(C)(C)C)=O)CC(O)=O)=O)C=C1)SCC2=CC=C(C=C2)OC
Biological Activity: BOC-PNA-thioU(PMB)-OH is a peptide nucleic acid (PNA) monomer characterized by a PMB protecting group on its thiouracil, which enhances its binding affinity to adenine. BOC-PNA-thioU(PMB)-OH exhibits excellent resistance to enzymatic degradation and strong hybridization properties, making it valuable for applications in gene diagnosis, antisense therapy, and other molecular biology fields requiring higher binding strength and greater functionalization.
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Boc-PNA-thioU(PMB)-OH | BOC-PNA-thioU(PMB)-OH is a peptide nucleic acid (PNA) monomer characterized by a PMB protecting group on its thiouracil, which enhances its binding affinity to adenine. BOC-PNA-thioU(PMB)-OH exhibits excellent resistance to enzymatic degradation and strong hybridization properties, making it valuable for applications in gene diagnosis, antisense therapy, and other molecular biology fields requiring higher binding strength and greater functionalization. | |||||||||||||||||||||
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Keywords
