19 Results for "

acarbose

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "acarbose" in MCE Product Catalog:

13
13 Cited Publications
Cat. No.: HY-B0089
CAS No.: 56180-94-0
Synonyms: BAY g 5421
Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .
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Cat. No.: HY-B0089R
CAS No.: 56180-94-0
Synonyms: BAY g 5421 (Standard)
Acarbose (Standard) is the analytical standard of Acarbose. This product is intended for research and analytical applications. Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .
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Cat. No.: HY-B0089S
CAS No.: 1260619-60-0
Synonyms: BAY g 5421-d4
Acarbose-d4 (BAY g 5421-d4) is deuterium labeled Acarbose. Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .
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Cat. No.: HY-B0089A
CAS No.: 1221158-13-9
Synonyms: Bay-g 5421 sulfate
Acarbose (BAY g 5421) sulfate, antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose sulfate can potentiate the hypoglycemic effects of sulfonylureas or insulin .
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Cat. No.: HY-131504A
CAS No.: 38231-86-6
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

Valienamine is the alpha-glucosidase inhibitor. Valienamine is the key functional component of many natural glycosidase inhibitors including the crop protectant validamycin A and the antidiabetic agent acarbose .
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Cat. No.: HY-121323R
CAS No.: 4430-36-8
Acarbose (Standard) is the analytical standard of Acarbose. This product is intended for research and analytical applications. Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .
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Cat. No.: HY-161782
CAS No.: 3049575-16-5
Target:  

Amylases

Research Areas:  

Metabolic Disease

α-Amylase-IN-7 (Compound 6e) is an inhibitor for α-Amylase with an IC50 of 40 μM. α-Amylase-IN-7 exhibits potential as an antidiabetic agent .
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Cat. No.: HY-E72048
Research Areas:  

Others

Acarbose 7IV-phosphotransferase (EC 2.7.1.187) is a transferase that can convert acarbose and ATP into acarbose 7(IV)-phosphate, ADP and H +.
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Cat. No.: HY-168462
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-82 (compound 8l) is a potent inhibitor of α-Glucosidase, with the IC50 of 13.66 μM. α-Glucosidase-IN-82 exhibits a 52-fold increase in inhibitory activity relative to Acarbose (HY-B0089) .
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Cat. No.: HY-162639
CAS No.: 1624628-01-8
α-Glucosidase-IN-68 (Compound 2) is an inhibitor for α-Glucosidase, AChE, and BChE, with IC50 of 0.251, 0.774 and 0.793 μM, respectively. α-Glucosidase-IN-68 exhibits antioxidant efficacy, with IC50 of 0.69 μM and 0.02 μM, in DPPH and ABTS experiments. α-Glucosidase-IN-68 exhibits antidiabetic effect in Streptozotocin (HY-13753)-induced diabetic rat models .
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Cat. No.: HY-147718
CAS No.: 111316-33-7
Target:  

Glutaminase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-5 (compound 8) is a potent α-glucosidase inhibitor with an IC50 of 57.9 µM. α-Glucosidase-IN-5 has the potential for the research of diabetes mellitus .
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Cat. No.: HY-147964
CAS No.: 735273-33-3
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-9 (compound 7) is a potent α-glucosidase inhibitor, with an IC50 of 55.6 μM. α-Glucosidase-IN-9 can be used for type II diabetes research .
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Cat. No.: HY-147965
CAS No.: 2586282-68-8
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-10 (compound 13) is a potent α-glucosidase inhibitor, with an IC50 of 92.7 μM. α-Glucosidase-IN-10 can be used for type II diabetes research .
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Cat. No.: HY-170606
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-79 (Compound 4d9) is a non-competitive α-Glucosidase inhibitor with an IC50 of 2.11 μM, which is more potent than existing α-Glucosidase inhibitors such as Acarbose (HY-B0089) (IC50 of 327.0 μM) and HXH8r (IC50 of 15.32 μM). α-Glucosidase-IN-79 is non-cytotoxic to human normal hepatocyte (LO2) cells and shows good metabolic stability in rat plasma. α-Glucosidase-IN-79 holds promise for research into type 2 diabetes .
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Cat. No.: HY-176221
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-92 (compound 14b) is a non-competitive inhibitor targeting α-glucosidase (IC50=64.0 μM), with better inhibitory potency than Acarbose (HY-B0089) (IC50=750 μM). α-Glucosidase-IN-92 has good oral bioavailability and can cross the blood-brain barrier. α-Glucosidase-IN-92 can delay carbohydrate hydrolysis and reduce postprandial blood glucose. α-Glucosidase-IN-92 can be used in anti-glycemic research for type 2 diabetes .
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Cat. No.: HY-178170
Target:  

Amylases Glycosidase

Research Areas:  

Metabolic Disease

α-Amylase/α-Glucosidase-IN-22 is an inhibitor of α-Amylase and α-Glucosidase with IC50 values of 1.71 and 10.36 nM (5 and 23.8 folds more potent than Acarbose (HY-B0089)). α-Amylase/α-Glucosidase-IN-22 can be used for the researches of metabolic disease, such as diabetes .
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Cat. No.: HY-E71525
Research Areas:  

Others

2-epi-5-epi-Valiolone 7-kinase (EC 2.7.1.188) is involved in the biosynthesis of the oligosaccharide acarbose.
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Cat. No.: HY-E71526
Research Areas:  

Others

2-epi-5-epi-Valiolone 7-phosphate 2-epimerase (EC 5.1.3.35) is involved in the biosynthesis of the α-glucosidase inhibitor acarbose.
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Cat. No.: HY-181476
CAS No.: 3095548-30-1
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-113 is an α-glucosidase inhibitor with an IC50 of 17.52 μM. α-Glucosidase-IN-113 shows antiglycating activity and inhibits advanced glycation end-product formation. α-Glucosidase-IN-113 can be used for the research of type 2 diabetes .
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