α-Glucosidase-IN-68
α-Glucosidase-IN-68 (Compound 2) is an inhibitor for α-Glucosidase, AChE, and BChE, with IC50 of 0.251, 0.774 and 0.793 μM, respectively. α-Glucosidase-IN-68 exhibits antioxidant efficacy, with IC50 of 0.69 μM and 0.02 μM, in DPPH and ABTS experiments. α-Glucosidase-IN-68 exhibits antidiabetic effect in Streptozotocin (HY-13753)-induced diabetic rat models.
For research use only. We do not sell to patients.
- CAS No.: 1624628-01-8
- Formula: C32H26F4N2O2
- Molecular Weight:546.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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α-Glucosidase 0.251 μM (IC50) |
AChE 0.774 μM (IC50) |
BChE 0.793 μM (IC50) |
Chemical Information
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CAS No. 1624628-01-8
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Molecular Weight 546.55
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Formula C32H26F4N2O2
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SMILES
O=C(C1=C(NC2=CC=C(F)C=C2)CC(C3=CC=C(F)C=C3)N(C4=CC=C(F)C=C4)C1C5=CC=C(F)C=C5)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
α-Glucosidase-IN-68 Related Classifications
HY-162639 Related Classifications
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