43 Results for "

acidic polypeptide

" in MedChemExpress (MCE) Product Catalog:
Products (43)

43 Results for "acidic polypeptide" in MCE Product Catalog:

25
25 Publications Verification
Cat. No.: HY-P1731C
Synonyms: LY3298176 sodium
Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide sodium exerts anti-apoptotic and pro-differentiation effects via the pAkt/CREB/BDNF cascade and miRNA in neurons; in the heart, it promotes BCAA catabolism and inhibits the mTOR pathway by mediating the dephosphorylation of BCKDHA; meanwhile, it effectively reduces insulin and leptin levels and suppresses inflammatory responses at the systemic level. Tirzepatide sodium can be used for research on myocardial infarction, colon cancer, diabetes, diabetic cognitive impairment, neurodegeneration, diabetes-related neuropathy, and obesity .
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5
5 Cited Publications
Cat. No.: HY-P2974
CAS No.: 39445-21-1
Synonyms: EC 3.4.21.36; Pancreatopeptidase E
Target:  

Elastase

Research Areas:  

Metabolic Disease

Elastase, Porcine pancreas (EC 3.4.21.36) is a single polypeptide chain of 240 amino acid residues, derived from pig pancreas. Elastase, Porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. Elastase from porcine pancreas can induce emphysema in hamsters .
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Cat. No.: HY-W011819
CAS No.: 821-38-5
Tetradecanedioic acid is an endogenous metabolite and belongs to the class of organic compounds known as long-chain fatty acids. Tetradecanedioic acid is an endogenous biomarker for assessing the activity of organic anion transporting polypeptides (OATPs) .
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Cat. No.: HY-P0047
CAS No.: 147732-56-7
Target:  

Peptides

Research Areas:  

Others

Palmitoyl tripeptide-1 is a fatty acid modified polypeptide. Palmitoyl Tripeptide-1 has good wrinkle-removing effect .
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Cat. No.: HY-W018004
CAS No.: 1190-49-4
L-Homocitrulline is a carbamoylated derivative amino acid and a structural analog of L-citrulline. L-Homocitrulline serves not only as an intermediate in polypeptide synthesis but also converts into a variety of cyclic derivatives under enzymatic or acidic conditions. The level of L-Homocitrulline is significantly elevated in the serum of patients with non-alcoholic fatty liver disease (NAFLD), with high diagnostic accuracy. L-Homocitrulline also exists in patients with related diseases such as hypercitrullinemia. L-Homocitrulline is a key biomarker for monitoring abnormal liver metabolism and is widely used in NAFLD research .
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Cat. No.: HY-172815
CAS No.: 3079913-81-5
Research Areas:  

Cancer

IDB-001 is a human ribosomal peptidyl transferase center (PTC) inhibitor that induces conformational changes and blocks translational elongation in specific sequence contexts through complementary interactions with Asp/Glu residues in nascent polypeptides. IDB-001 preferentially stalls ribosomes at positions containing acidic peptide motifs, thereby inhibiting cancer cell proliferation, and activates the integrated stress response via eIF2α phosphorylation at high concentrations. In addition, IDB-001 mildly triggers ribotoxic stress responses through phosphorylation of JNK and p38. IDB-001 has been applied to mechanistic studies of triple-negative breast cancer .
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Cat. No.: HY-E70004
CAS No.: 9068-59-1
Research Areas:  

Others

Microbial neutral proteinase is a zinc-containing metalloproteinase mainly produced by Bacillus and fungi. Its catalytic activity is highly dependent on divalent cations, and it remains active within the pH range of 5-8. Microbial neutral proteinase can specifically cleave peptide bonds within polypeptide chains, thereby degrading macromolecular proteins into small peptides or amino acids. It can be applied in various industrial fields including food processing, brewing, detergents, and light industry .
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Cat. No.: HY-P1777
CAS No.: 135861-49-3
Synonyms: Insulin-like Growth Factor I (24-41)
Target:  

IGF-1R

IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development .
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Cat. No.: HY-P3579
CAS No.: 11063-17-5
Synonyms: GIP (1-42), porcine
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Gastric Inhibitory Peptide (GIP (1-42)), porcine is a porcine glucose-dependent insulinotropic polypeptide and inhibitor of pentagastrin-stimulated gastric acid secretion. Gastric Inhibitory Peptide, porcine stimulates endogenous somatostatin release. Gastric Inhibitory Peptide, porcine acts in a dose- and time-dependent manner in conscious, chronic gastric fistula-equipped rats .
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Cat. No.: HY-W011819S
CAS No.: 130348-88-8
Tetradecanedioic acid-d24 is the deuterium labeled Tetradecanedioic acid . Tetradecanedioic acid is an endogenous metabolite and belongs to the class of organic compounds known as long-chain fatty acids. Tetradecanedioic acid can act as a candidate biomarker for organic anion-transporting polypeptide mediated agent-agent interactions .
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Cat. No.: HY-P0047A
CAS No.: 2757690-14-3
Target:  

Peptides

Research Areas:  

Others

Palmitoyl tripeptide-1 hydrochloride is a fatty acid modified polypeptide. Palmitoyl Tripeptide-1 has good wrinkle-removing effect .
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Cat. No.: HY-D0193A
CAS No.: 2611-82-7
Synonyms: Acid Red 18 (85%); New Coccine (85%)
Ponceau 4R (85%) (Acid Red 18 (85%); New Coccine (85%)) is an orally active synthetic food colorant and a HSA-binding aggregator. Ponceau 4R (85%) binds to HSA, inducing its partial unfolding, conformational changes and aggregation. Ponceau 4R (85%) serves as a food colorant and can be used in research on diseases including type Ⅱ diabetes, Parkinson's disease, Huntington's disease and spongiform encephalopathy .
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Cat. No.: HY-P3649
CAS No.: 75590-15-7
Research Areas:  

Cardiovascular Disease

D-Val-Leu-Lys-chloromethylketone is a polypeptide containing three amino acids. D-Val-Leu-Lys-chloromethylketone can act as an anticoagulant .
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Cat. No.: HY-P3640
CAS No.: 178243-46-4
Target:  

Peptides

Research Areas:  

Cancer

MAGE-3 Antigen (167-176) (human) is a polypeptide containing eight amino acids. MAGE-3 Antigen (167-176) (human) is a human leukocyte antigen HLA-B44 molecules epitope encoded by melanoma antigen gene (MAGE) .
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Cat. No.: HY-P1441
CAS No.: 1609937-15-6
Target:  

Sodium Channel

Research Areas:  

Others

Mambalgin-1 is a toxin isolated from black mamba venom. Mambalgin-1 is a disulfide-rich polypeptide consisting of 57 amino acids and belongs to the family of three-finger toxins. Mambalgin-1 can bind to and stabilize ASICs (acid-sensing ion channels) in a physiologically relevant closed-channel conformation .
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Cat. No.: HY-P3780
CAS No.: 1802078-25-6
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (36-42) is the 36-42 fragment of Amyloid β-Protein. β-amyloid, a polypeptide made up of 36-43 amino acids, is the main component of amyloid plaques found in the brains of people with Alzheimer's disease. β-amyloid oligomers (Aβos) plays A key role in the progression of Alzheimer's disease (AD) by inducing neuronal damage and cognitive impairment .
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Cat. No.: HY-P3655
CAS No.: 142582-60-3
Target:  

Calcium Channel

Research Areas:  

Others

Agelenin is a polypeptide composed of 35 amino acids. Agelenin could be isolated from the Agelenidae spider Agelena opulenta. Agelenin has structural similarity to insect-specific calcium channel inhibitor .
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Cat. No.: HY-P3961
CAS No.: 81478-67-3
Target:  

Peptides

Research Areas:  

Others

[Tyr0] Thymus Factor is a polypeptide with 10 amino acids .
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Cat. No.: HY-P11400
Target:  

Peptides

Research Areas:  

Infection

Pilosulin-2 (49-75) is a polypeptide composed of 27 amino acids. Pilosulin-2 (49-75) can be isolated from the venom of Myrmecia pilosula.
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Cat. No.: HY-P5300A
Target:  

Peptides

Research Areas:  

Others

YNPCVMYL (Thioester: Cys4-Leu8) TFA is a polypeptide chain of the YNPCVMYL sequence. The link between the fourth and eighth amino acids in the sequence has the properties of a thioester, which is formed between cysteine (Cys4) and leucine (Leu8).
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