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Isoforms Recommended:	Caspase 10

Results for "

caspase-10

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Caspase (8) Apoptosis (4) DNA Methyltransferase (1) Endogenous Metabolite (1) HIF/HIF Prolyl-Hydroxylase (1) Parasite (1) Quinone Reductase (2) Reference Standards (1)
By Research Areas:	Cancer (6) Infection (1) Neurological Disease (1)

Inhibitors & Agonists

Fluorescent Dyes

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Targets Recommended: Caspase

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-103667

2-HBA 3 Publications Verification	Quinone Reductase Caspase	Cancer
2-HBA is a potent inducer of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) which can also activate *caspase-3* and *caspase-10*.

HY-P1169

Ac-IETD-AFC 1 Publications Verification	Caspase	Others
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .

HY-125305

Z-AEVD-FMK	Caspase Apoptosis	Cancer
Z-AEVD-FMK is a *caspase-10* inhibitor. Z-AEVD-FMK can inhibit the activation of Bid and the release of apoptosis-inducing factor (AIF) in mitochondria in cells, resulting in a significant decrease in the number of apoptotic cells .

HY-N2802

Euptox A 9-Oxo-10,11-dehydroageraphorone	Apoptosis Caspase Parasite	Infection Cancer
Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells .

HY-P10162A

Ac-DMQD-AMC TFA	Caspase	Others
Ac-DMQD-AMC TFA is a fluorogenic substrate for caspase-3 or caspase-10. Similar to Ac-DEVD-AMC, it releases the AMC (7-amino-4-methylcoumarin) fluorophore, resulting in fluorescence. Ac-DMQD-AMC TFA can be used to measure caspase activity in in vitro apoptosis monitoring .

HY-15091

Anisperimus LF-150195	Endogenous Metabolite	Neurological Disease
Anisperimus (LF-150195) is an immunosuppressant with the activity of enhancing activation-induced T cell death. Anisperimus enhances the sensitivity of T cells to anti-CD95 antibodies and other inducers by promoting the activation of caspase-8 and caspase-10 at the level of the death-inducing signaling complex (DISC). Anisperimus also promotes the development of Foxp3-expressing regulatory CD4 T cells, thereby preventing central nervous system autoimmunity .

HY-103667R

2-HBA (Standard)	Quinone Reductase Reference Standards Caspase	Cancer
2-HBA (Standard) is the analytical standard of 2-HBA (HY-103667). This product is intended for research and analytical applications. 2-HBA is a potent inducer of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) which can also activate caspase-3 and caspase-10.

HY-181955

MS1129	Apoptosis DNA Methyltransferase HIF/HIF Prolyl-Hydroxylase Caspase	Cancer
MS1129 is a DNMT degrader that induces proteasomal degradation of DNMT1, DNMT3A and DNMT3B proteins. MS1129 upregulates TRAIL, DR4 and DR5 proteins, downregulates the decoy receptor DcR2, and activates TRAIL-dependent apoptosis via the HIF-1/2 and Caspase-10 pathways. MS1129 is applicable to the research of VHL-deficient clear cell renal cell carcinoma .

HY-P11865

Ac-ATS010-KE	Caspase Apoptosis	Cancer
Ac-ATS010-KE is a selective polypeptide inhibitor of *caspase-3. Ac-ATS010-KE protects cells from FasL-induced apoptosis. The unmethylated form of Ac-ATS010-KE exhibits better cell viability than the fully methylated form. Ac-ATS010-KE can be used in research on cancers such as colorectal cancer and the development of caspase*-3-targeted molecular probes .

Cat. No.	상품명	Type

HY-P1169

Ac-IETD-AFC 1 Publications Verification	Fluorescent Dyes
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .

Cat. No.	상품명	Target	Research Area

HY-P1169

Ac-IETD-AFC 1 Publications Verification	Caspase	Others
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .

HY-P10162A

Ac-DMQD-AMC TFA	Caspase	Others
Ac-DMQD-AMC TFA is a fluorogenic substrate for caspase-3 or caspase-10. Similar to Ac-DEVD-AMC, it releases the AMC (7-amino-4-methylcoumarin) fluorophore, resulting in fluorescence. Ac-DMQD-AMC TFA can be used to measure caspase activity in in vitro apoptosis monitoring .

HY-P11865

Ac-ATS010-KE	Caspase Apoptosis	Cancer
Ac-ATS010-KE is a selective polypeptide inhibitor of *caspase-3. Ac-ATS010-KE protects cells from FasL-induced apoptosis. The unmethylated form of Ac-ATS010-KE exhibits better cell viability than the fully methylated form. Ac-ATS010-KE can be used in research on cancers such as colorectal cancer and the development of caspase*-3-targeted molecular probes .

Euptox A 9-Oxo-10,11-dehydroageraphorone	Pongamia pinnata (L.) Pierre Terpenoids Sesquiterpenes Plants Compositae Source Classification	Apoptosis Caspase Parasite
Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells .

Recombinant Proteins Recommended:

Caspase-10

Cat. No.	Compare	상품명	Species	Source	Image

HY-P705693

	Caspase-10/CASP10 Protein, Human (His-GST) rHucaspase-10, His; caspase-10; CASP-10; Apoptotic Protease Mch-4; ICE-Like Apoptotic Protease 4; CASP10; MCH4	Human	E. coli
	Caspase-10/CASP10 Protein, Human (His-GST) is an approximately 54.2 kDa caspase-10 protein with a His-GST-tag, expressed in E. coli. Caspase-10 belongs to the caspase family and involved in the execution-phase of cell apoptosis.

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Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

Host:	Rabbit (3)
Reactivity:	Human (3)
Application:	IHC-P (3) IP (3) WB (3) FC (1)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (2)

Cat. No.	Compare	상품명	Application	Reactivity	Image

HY-P80044

	Caspase-10 Antibody (YA559)	WB, IHC-P, FC, IP	Human
	Caspase-10 Antibody (YA559) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspase-10.

HY-P82621

	Caspase-10 Antibody (YA2366) CASP10; MCH4; caspase-10; CASP-10; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4	WB, IHC-P, IP	Human
	Caspase-10 Antibody (YA2366) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspase-10.

HY-P82621A

	Caspase-10 Antibody (YA2366)(PBS only) CASP10; MCH4; caspase-10; CASP-10; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4	WB, IHC-P, IP	Human
	Caspase-10 Antibody (YA2366) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspase-10.

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SwissProt ID
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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caspase-10

Inhibitors & Agonists

Fluorescent Dyes

Peptides

NaturalProducts

Recombinant Proteins

Antibodies

Natural
Products