2379342-67-1
Chemical Structure
Ac-ATS010-KE
- CAS No.: 2379342-67-1
- Formula:C43H41F5N6O12S
- Molecular Weight:960.88
InChIKey: GIKNNIUUHLGPPS-ZIUUJSQJSA-N
SMILES: FC(C(F)=C(C(F)=C1F)F)=C1C[C@H](NC([C@H](CC(O)=O)NC([C@@H](NC(C)=O)CC2=CN=CC=C2)=O)=O)C(N[C@H](C(N[C@@H](CC(O)=O)C(COC(C3=CC=C(S3)C)=O)=O)=O)CC4=CC=CC=C4)=O
Biological Activity: Ac-ATS010-KE is a selective polypeptide inhibitor of caspase-3. Ac-ATS010-KE protects cells from FasL-induced apoptosis. The unmethylated form of Ac-ATS010-KE exhibits better cell viability than the fully methylated form. Ac-ATS010-KE can be used in research on cancers such as colorectal cancer and the development of caspase-3-targeted molecular probes[1].
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Ac-ATS010-KE | Ac-ATS010-KE is a selective polypeptide inhibitor of caspase-3. Ac-ATS010-KE protects cells from FasL-induced apoptosis. The unmethylated form of Ac-ATS010-KE exhibits better cell viability than the fully methylated form. Ac-ATS010-KE can be used in research on cancers such as colorectal cancer and the development of caspase-3-targeted molecular probes. | |||||||||||||||||||||
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