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Results for "

core α1

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-E70134
    Endo-β-N-acetylglucosaminidase F3

    Endo F3

    		 Others Metabolic Disease
    Endo-β-N-acetylglucosaminidase D (Endo F3) cleaves free or Asparagine-linked triantennary oligosaccharides or α1-6 fucosylated biantennary oligosaccharides, as well as triamnnosyl chitobiose core structures [1].
    Endo-β-N-acetylglucosaminidase F3
  • HY-E70555
    PNGase A

    		Glycosidase Others
    PNGase A is a β-aspartylglucosaminidase and N-glycan-releasing enzyme. PNGase A catalyzes hydrolysis reactions to release the N-glycan moiety from glycoproteins or glycopeptides. PNGase A releases N-linked oligosaccharides containing core α-1,3 fucose from glycopeptides. PNGase A undergoes self-deglycosylation, which may cause contamination of endogenous glycan structures in N-glycan analysis. PNGase A cannot be heterologously expressed in recombinant expression systems; it can be extracted and purified from almond seeds [1].
    PNGase A
  • HY-E70029
    α-1,6-Fucosidase, lactobacillus casei

    		Others Others
    alpha-1,6-Fucosidase (LpAlfC(E274A)) (EC 3.2.1.51) cleaves branched non-reducing terminal fucose, linked α(1-6) to the core N-acetylglucosamine of N-linked oligosaccharides. alpha-1,6-Fucosidase (LpAlfC(E274A)) is useful for determining core fucosylation [1].
    α-1,6-Fucosidase, lactobacillus casei
  • HY-E70887
    Broad-specificity fucosidase O

    FucO

    		 Glycosidase Others
    Broad-specificity fucosidase O (FucO) is a α-fucosidase that can efficiently remove α1-6- and α1-3-linked core fucose from N-glycans [1].
    Broad-specificity fucosidase O
  • HY-E70140
    α-1,4-N-Acetylglucosaminyltransferase 4

    EC 2.4.1; A4GNT

    		 Bacterial Infection
    α-1,4-N-Acetylglucosaminyltransferase 4 (EC 2.4.1, A4GNT) catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans and suppresses H. pylori growth [1].
    α-1,4-N-Acetylglucosaminyltransferase 4
  • HY-183552
    mCPX

    		HIF/HIF Prolyl-Hydroxylase EBV Drug Intermediate Infection Cancer
    mCPX is a prodrug of the antifungal agent Ciclopirox olamine (CPX) (HY-B0450A). CPX exhibits bacteriostatic and iron-chelating activities, while mCPX enhances the iron stability of CPX. mCPX inherits the core mechanism pathway of CPX and can induce EBV lytic reactivation in EBV + gastric cancer cells via the hypoxia pathway (HIF‑1α). mCPX is applicable to research related to EBV-positive gastric cancer [1].
    mCPX
  • HY-165413
    KST012174 hydrochloride

    		HIF/HIF Prolyl-Hydroxylase VEGFR Cancer
    KST012174 hydrochloride is a potent HIF-1α-p300/CBP interaction inhibitor with an IC50 of 107 μM. KST012174 hydrochloride completely blocks the binding of HIF-1α to p300 protein at a concentration of 100 μM, without affecting the expression stability of HIF-1α protein itself. By directly interfering with the binding between the C-terminal transactivation domain (C-TAD) of HIF-1α and the CH1 domain of p300, KST012174 inhibits the transcriptional activation function of HIF-1α, thereby significantly downregulating the mRNA expression level of its downstream target gene VEGF and exerting core activity in inhibiting tumor angiogenesis. KST012174 hydrochloride is applicable for research on cancer occurrence and development as well as hypoxia pathway-targeted strategies [1] .
    KST012174 hydrochloride

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