mCPX
mCPX is a prodrug of the antifungal agent Ciclopirox olamine (CPX) (HY-B0450A). CPX exhibits bacteriostatic and iron-chelating activities, while mCPX enhances the iron stability of CPX. mCPX inherits the core mechanism pathway of CPX and can induce EBV lytic reactivation in EBV+ gastric cancer cells via the hypoxia pathway (HIF‑1α). mCPX is applicable to research related to EBV-positive gastric cancer.
For research use only. We do not sell to patients.
- CAS No.: 1351572-56-9
- Formula: C14H19NO3
- Molecular Weight:249.31
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
In Vitro
mCPX induces EBV lytic cycle in SNU719 and AGSBX1 EBV+ gastric cancer cell lines with activity comparable to CPX, and has significantly greater resistance to iron-mediated inactivation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Parmacokinetics
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1351572-56-9
-
Molecular Weight 249.31
-
Formula C14H19NO3
-
SMILES
O=C(C)ON(C(C1CCCCC1)=CC(C)=C2)C2=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
mCPX Related Classifications
HY-183552 Related Classifications
Powered by Bioz