7 Results for "

cyclic decapeptide

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "cyclic decapeptide" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-100731
CAS No.: 79217-60-0
Purity:  99.31%
Target:  

Cyclophilin

Research Areas:  

Inflammation/Immunology Cancer

Cyclosporin is a cyclic decapeptide that could be isolated form the soil fungi Tolypocladium inflatum. Cyclosporin is an immunosuppressant thought to bind to cyclophilin in T-lymphocytes .
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Cat. No.: HY-P1755A
Target:  

MDM-2/p53

Research Areas:  

Cancer

p53 (17-26) acetate is a peptide derived from the P53 MDM2 binding domain, with a Kd of 50 nM for MDM2. p53 (17-26) acetate causes cell lysis by damaging cancer cells and nuclear membranes, and induces cancer cell necrosis. p53 (17-26) acetate exhibits antitumor activity and is applicable to research related to pancreatic cancer .
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Cat. No.: HY-P4320
CAS No.: 166184-23-2
Target:  

Integrin

Research Areas:  

Cancer

Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge: Cys1-Cys10), a decapeptide containing a cyclic RGD active sequence, is an Integrin αIIbβ3 antagonist that inhibits platelet and Adhesion of proMMP-13 .
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Cat. No.: HY-103289
CAS No.: 235082-52-7
Purity:  99.15%
MEN 11270, a cyclic decapeptide, is a B2 kinin receptor antagonist. MEN 11270 bound with high-affinity to the B2 kinin receptor constitutively expressed by WI38 human fibroblasts, inhibiting 3H-bradykinin (BK) with a pKi value of 10.3 .
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Cat. No.: HY-N14354
CAS No.: 114562-40-2
Ferrocin B is an iron-containing cyclic decapeptide antibiotic found in the bacterium Pseudomonas fluorescens YK-310, exhibiting strong antibacterial activity primarily against Gram-negative bacteria, with particularly potent inhibitory effects on Pseudomonas aeruginosa. In a mouse infection model, Ferrocin B shows a half effective dose (ED50) of 0.593 mg/kg against P. aeruginosa. Ferrocin B holds potential for research in the field of anti-infective therapies .
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Cat. No.: HY-P11889
CAS No.: 1481-70-5
Target:  

Bacterial

Research Areas:  

Infection

Tyrocidine A is an amphipathic cyclic decapeptide natural product, as well as a membrane-disrupting agent and an antibacterial agent. Tyrocidine A exhibits moderate activity against Gram-positive bacteria. Tyrocidine A can insert into bacterial cell membranes, form porous channels, disrupt membrane integrity and induce bacterial cell death. Tyrocidine A can be used in studies related to bacterial infections .
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Cat. No.: HY-P11889A
Target:  

Bacterial

Research Areas:  

Infection

Tyrocidine A TFA is an amphipathic cyclic decapeptide natural product, as well as a membrane-disrupting agent and an antibacterial agent. Tyrocidine A TFA exhibits moderate activity against Gram-positive bacteria. Tyrocidine A TFA can insert into bacterial cell membranes, form porous channels, disrupt membrane integrity and induce bacterial cell death. Tyrocidine A TFA can be used in studies related to bacterial infections .
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