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cysteamine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (6) Autophagy (3) Biochemical Assay Reagents (3) Caspase (3) Drug Derivative (1) Endogenous Metabolite (3) Glutaminase (3) Isotope-Labeled Compounds (1) Keap1-Nrf2 (1) Na+/K+ ATPase (1) Orexin Receptor (OX Receptor) (1) Phosphatase (1) Phospholipase (1) Reactive Oxygen Species (ROS) (3) Reference Standards (2) Sigma Receptor (1)
By Research Areas:	Cancer (7) Metabolic Disease (6) Neurological Disease (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-77591

Cysteamine hydrochloride 2 Publications Verification 2-Aminoethanethiol hydrochloride; 2-Mercaptoethylamine hydrochloride	Autophagy Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite	Metabolic Disease Cancer
Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.

HY-124476

Cystamine 5 Publications Verification	Caspase Glutaminase Apoptosis	Cancer
Cystamine is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC₅₀ value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) .

HY-101794

2-(Pyridyldithio)ethylamine hydrochloride 4 Publications Verification (S)-2-Pyridylthio cysteamine Hydrochloride	Biochemical Assay Reagents	Others
2-(Pyridyldithio)ethylamine hydrochloride is a novel disulfide intercalating cross-linking reagent.

HY-W020050

Cystamine dihydrochloride 5 Publications Verification	Caspase Glutaminase Apoptosis	Neurological Disease Cancer
Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC₅₀ value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) .

HY-77591S

Cysteamine-d4 hydrochloride 2-Aminoethanethiol-d4 hydrochloride; 2-Mercaptoethylamine-d4 hydrochloride	Isotope-Labeled Compounds Autophagy Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite	Metabolic Disease Cancer
Cysteamine-d₄ (hydrochloride) is the deuterium labeled Cysteamine hydrochloride. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.

HY-P4119

Pep-1-Cysteamine	Biochemical Assay Reagents	Others
Pep-1-Cysteamine is an amphipathic chimeric cell-penetrating peptide. Pep-1-Cysteamine can penetrate biological membranes in an energy-independent manner without forming transmembrane pores, and efficiently deliver active proteins into cells, with its translocation dominated by electrostatic interactions and membrane perturbation .

HY-153340

I-152	Keap1-Nrf2	Metabolic Disease
I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). I-152 activates NRF2 and ATF4 signals. I-152 has anti-proliferative properties .

HY-77591R

Cysteamine hydrochloride (Standard) 2-Aminoethanethiol hydrochloride (Standard); 2-Mercaptoethylamine hydrochloride (Standard)	Reference Standards Autophagy Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite	Metabolic Disease Cancer
Cysteamine (hydrochloride) (Standard) is the analytical standard of Cysteamine (hydrochloride). This product is intended for research and analytical applications. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.

HY-P1341

OXA(17-33) Orexin A (17-33) (human, mouse, rat, bovine)	Orexin Receptor (OX Receptor) Sigma Receptor Phospholipase	Neurological Disease
OXA (17-33) (Orexin A (17-33) (human, mouse, rat, bovine)) is the shortest active orexin peptide that selectively targets OX1 (EC₅₀=8.29 nM), with 23-fold selectivity for the OX1 receptor over the OX2 receptor. The activity of OXA (17-33) depends on the Tyr17, Leu20, Asn25, His26 residues and the spatial conformation of the α-helix. OXA (17-33) activates signaling pathways involving inositol-1,4,5-trisphosphate receptor (IP3R), phospholipase D (PL-D) and choline-Sigma-1R, thereby increasing the cytoplasmic Ca ²⁺ level in nucleus accumbens neurons, an effect that is blocked by Sigma-1R antagonists. OXA (17-33) serves as an important biological probe for investigating the function of the OX1 receptor. OXA (17-33) can be modified via incorporation of mixed disulfide bonds of homocysteine and cysteamine, and is widely used in studies related to insomnia and narcolepsy .

HY-W141781

Cysteamine S-phosphate sodium Cystaphos sodium	Phosphatase	Metabolic Disease
Cysteamine S-phosphate (Cystaphos) sodium can be hydroIyzed to Cysteamine by human alkaline phosphatases. Cysteamine is an orally active agent for the research of nephropathic cystinosis and an antioxidant .

HY-126751

DBM-819	Na+/K+ ATPase	Metabolic Disease
DBM-819 is a reversible inhibitor of H⁺/K⁺-ATPase (H ⁺/K ⁺-ATPase), with an IC₅₀ value of 5 μM. DBM-819 can reversibly block gastric acid secretion by inhibiting the proton pump in the gastric mucosa. It shows significant protective effects against duodenal ulcers induced by Cysteamine (HY-77591), gastric ulcers induced by Indomethacin (HY-14397), and gastric ulcers induced by Aspirin (HY-14654), with EC₅₀ values of 6, 3.1, and 4 mg/kg respectively. DBM-819 can be used in ulcer prevention research .

HY-W020050S

Cystamine-d8 dihydrochloride	Apoptosis Caspase Glutaminase	Cancer
Cystamine-d₈ (dihydrochloride） is the deuterium labeled Cystamine (dihydrochloride） . Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC₅₀ value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) .

HY-101794R

2-(Pyridyldithio)ethylamine hydrochloride (Standard) (S)-2-Pyridylthio cysteamine Hydrochloride (Standard)	Biochemical Assay Reagents Reference Standards	Others
2-(Pyridyldithio)ethylamine hydrochloride (Standard) ((S)-2-Pyridylthio Cysteamine Hydrochloride (Standard)) is the analytical standard of 2-(Pyridyldithio)ethylamine hydrochloride (HY-101794). This product is intended for research and analytical applications. 2-(Pyridyldithio)ethylamine hydrochloride is a novel disulfide intercalating cross-linking reagent.

HY-105433

Perrimustine	Drug Derivative	Cancer
Perrimustine is a cysteamine (CysA) derivative with potent antitumor activity. Perrimustine exhibits significant effect on B16 melanoma and metastasized melanoma cells by causing DNA damage. Perrimustine exhibits antitumor effects in mice bearing various cancers, including lung carcinoma, leukemia, lymphoma, melanoma, colon carcinoma, and glioma. Perrimustine can be used for cancer research, such as melanoma and leukemia .

Cat. No.	Product Name	Type

HY-101794

2-(Pyridyldithio)ethylamine hydrochloride 4 Publications Verification (S)-2-Pyridylthio cysteamine Hydrochloride	Biochemical Assay Reagents
2-(Pyridyldithio)ethylamine hydrochloride is a novel disulfide intercalating cross-linking reagent.

HY-101794R

2-(Pyridyldithio)ethylamine hydrochloride (Standard) (S)-2-Pyridylthio cysteamine Hydrochloride (Standard)	Biochemical Assay Reagents
2-(Pyridyldithio)ethylamine hydrochloride (Standard) ((S)-2-Pyridylthio Cysteamine Hydrochloride (Standard)) is the analytical standard of 2-(Pyridyldithio)ethylamine hydrochloride (HY-101794). This product is intended for research and analytical applications. 2-(Pyridyldithio)ethylamine hydrochloride is a novel disulfide intercalating cross-linking reagent.

Cat. No.	Product Name	Target	Research Area

HY-P4119

Pep-1-Cysteamine	Biochemical Assay Reagents	Others
Pep-1-Cysteamine is an amphipathic chimeric cell-penetrating peptide. Pep-1-Cysteamine can penetrate biological membranes in an energy-independent manner without forming transmembrane pores, and efficiently deliver active proteins into cells, with its translocation dominated by electrostatic interactions and membrane perturbation .

HY-P1341

OXA(17-33) Orexin A (17-33) (human, mouse, rat, bovine)	Orexin Receptor (OX Receptor) Sigma Receptor Phospholipase	Neurological Disease
OXA (17-33) (Orexin A (17-33) (human, mouse, rat, bovine)) is the shortest active orexin peptide that selectively targets OX1 (EC₅₀=8.29 nM), with 23-fold selectivity for the OX1 receptor over the OX2 receptor. The activity of OXA (17-33) depends on the Tyr17, Leu20, Asn25, His26 residues and the spatial conformation of the α-helix. OXA (17-33) activates signaling pathways involving inositol-1,4,5-trisphosphate receptor (IP3R), phospholipase D (PL-D) and choline-Sigma-1R, thereby increasing the cytoplasmic Ca ²⁺ level in nucleus accumbens neurons, an effect that is blocked by Sigma-1R antagonists. OXA (17-33) serves as an important biological probe for investigating the function of the OX1 receptor. OXA (17-33) can be modified via incorporation of mixed disulfide bonds of homocysteine and cysteamine, and is widely used in studies related to insomnia and narcolepsy .

HY-P4119A

*Pep-1-Cysteamine* TFA**	Peptides	Others
Pep-1-Cysteamine TFA is a chimeric cell-penetrating peptide (CPP) with a primary amphipathicity. Pep-1-Cysteamine TFA has the ability to translocate across biological membranes and introduce active proteins inside cells .

HY-W141781

Cysteamine S-phosphate sodium Cystaphos sodium	Phosphatase	Metabolic Disease
Cysteamine S-phosphate (Cystaphos) sodium can be hydroIyzed to Cysteamine by human alkaline phosphatases. Cysteamine is an orally active agent for the research of nephropathic cystinosis and an antioxidant .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-77591

Cysteamine hydrochloride 2 Publications Verification 2-Aminoethanethiol hydrochloride; 2-Mercaptoethylamine hydrochloride	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Autophagy Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.

HY-77591R

Cysteamine hydrochloride (Standard) 2-Aminoethanethiol hydrochloride (Standard); 2-Mercaptoethylamine hydrochloride (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Autophagy Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Cysteamine (hydrochloride) (Standard) is the analytical standard of Cysteamine (hydrochloride). This product is intended for research and analytical applications. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.

Cat. No.	Product Name	Chemical Structure

HY-77591S

Cysteamine-d4 hydrochloride
Cysteamine-d₄ (hydrochloride) is the deuterium labeled Cysteamine hydrochloride. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.

HY-W020050S

Cystamine-d8 dihydrochloride
Cystamine-d₈ (dihydrochloride） is the deuterium labeled Cystamine (dihydrochloride） . Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC₅₀ value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) .

Cystamine-d8 dihydrochloride

Cystamine-d₈ (dihydrochloride） is the deuterium labeled Cystamine (dihydrochloride） . Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC₅₀ value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) .

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cysteamine

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products