19 Results for "

dendrimer

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "dendrimer" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-148559
CAS No.: 1857340-78-3
Purity:  99.21%
Target:  

Liposome

Research Areas:  

Cancer

4A3-SC8 is a modular degradable dendrimer that enables small RNAs to extend survival in an aggressive liver cancer model .
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2
2 Cited Publications
Cat. No.: HY-152229
CAS No.: 1510653-27-6
Purity:  ≥98.0%
G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery .
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Cat. No.: HY-W007599
CAS No.: 2483-46-7
Target:  

Drug Derivative

Research Areas:  

Cancer

(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid is a polypeptide derivative, can be used to synthesis multifunctional amphiphilic peptide dendrimer for non-viral gene delivery in cancer research. (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid can be used in the preparation of organic substances that enhance the luminescence intensity of alkaline phosphatase substrates .
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Cat. No.: HY-168940B
CAS No.: 139729-28-5
NH2-PEG5000-COOH is a compound composed of an NH2 group, PEG units (MW = 2000) and a carboxyl group (-COOH) . NH2-PEG-COOH is widely used for surface modification and functionalization of polymer carriers or nanoparticles .
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Cat. No.: HY-W007695
CAS No.: 1072-84-0
Synonyms: 4-Imidazolecarboxylic acid
1H-Imidazole-4-carboxylic acid (4-Imidazolecarboxylic acid) is an organic compound containing an imidazole ring and a carboxyl group. 1H-Imidazole-4-carboxylic acid stabilizes specific forms of metal ions through coordination, thus influencing the progress of chemical reactions. 1H-Imidazole-4-carboxylic acid plays an important role in the hydrolysis of phosphate esters catalyzed by lanthanide metals. 1H-Imidazole-4-carboxylic acid can be used to modify dendrimers, changing the surface properties and catalytic performance of materials .
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Cat. No.: HY-W157376
CAS No.: 155773-72-1
Research Areas:  

Infection Cancer

PAMAM Dendrimer G0.0 amine is a pore-forming channel antagonist, including anthrax toxin protective antigen 63 (PA63, IC50 = 231 nM) and C. botulinum C2 toxin subunit (C2IIa, IC50 = 940 nM). At concentrations of 10 and 20 µM, PAMAM Dendrimer G0.0 amine reduces C2 toxin-induced death in HeLa cells. Additionally, PAMAM Dendrimer G0.0 amine is a chelator of nickel. In complexes with polysulfone membrane-bound chitosan, PAMAM Dendrimer G0.0 amine selectively captures and stores carbon dioxide (CO2) in a gas-feed system. PAMAM Dendrimer G0.0 amine has been used in the synthesis of PAMAM Dendrimer G0.5 Carboxylate (CAS 339334-01-9) and PAMAM Dendrimer G1.0 Amine (CAS 142986-44-5). PAMAM Dendrimer G0.0 amine can be used in research related to infections, cancer, and drug delivery systems .
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Cat. No.: HY-169474
CAS No.: 142986-44-5
Synonyms: PAMAM G1.0
Research Areas:  

Cancer

Starburst 1st Generation (PAMAM G1.0) is a Polyamidoamine (HY-164657; PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vitro. Starburst 1st Generation conjugated to di-n-dodecylamine and encapsulating 5-Fluorouracil (HY-90006) increase the solubility of 5-Fluorouracil and are cytotoxic to AGS gastric adenocarcinoma cells .
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Cat. No.: HY-168940
CAS No.: 139729-28-5
NH2-PEG1000-COOH is a compound composed of an NH2 group, PEG units (MW = 1000) and a carboxyl group (-COOH) . NH2-PEG-COOH is widely used for surface modification and functionalization of polymer carriers or nanoparticles .
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Cat. No.: HY-168940H
CAS No.: 139729-28-5
NH2-PEG5000-COOH is a compound composed of an NH2 group, PEG units (MW = 5000) and a carboxyl group (-COOH) . NH2-PEG-COOH is widely used for surface modification and functionalization of polymer carriers or nanoparticles .
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Cat. No.: HY-169047
CAS No.: 251970-28-2
Synonyms: PAMAM G1.5 carboxylate sodium
Target:  

SARS-CoV

Research Areas:  

Infection

PAMAM dendrimer G1.5 carboxylate (PAMAM G1.5 carboxylate) sodium is a polyanionic dendrimers comprising the terminal groups sodium carboxylate. PAMAM dendrimer G1.5 carboxylate shows antiviral activity with the MERS‐CoV plaque inhibition assay, with the inhibition rate of 40.5% .
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Cat. No.: HY-168940D
CAS No.: 139729-28-5
NH2-PEG400-COOH is a compound composed of an NH2 group, PEG units (MW = 400) and a carboxyl group (-COOH) . NH2-PEG-COOH is widely used for surface modification and functionalization of polymer carriers or nanoparticles .
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Cat. No.: HY-168940E
CAS No.: 139729-28-5
NH2-PEG600-COOH is a compound composed of an NH2 group, PEG units (MW = 600) and a carboxyl group (-COOH) . NH2-PEG-COOH is widely used for surface modification and functionalization of polymer carriers or nanoparticles .
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Cat. No.: HY-169477
CAS No.: 339334-01-9
Research Areas:  

Cancer

PAMAM Dendrimer G0.5 Carboxylate sodium is a polyamidoamine (PAMAM) dendrimer with carboxylate termini. PAMAM Dendrimer G0.5 Carboxylate sodium conjugated with DACHPt is cytotoxic to A2780 ovarian cancer cells, MCF-7 breast cancer cells, Caco-2 colon cancer cells and BJ fibroblasts with IC50 values of 0.03, 1.6, 0.18 and 3 µM, respectively .
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Cat. No.: HY-163203
CAS No.: 1402224-73-0
Target:  

Bacterial

Research Areas:  

Infection

DDC18-8A is an amphiphilic dendrimer that exhibits high antibacterial and antibiofilm efficacy .
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Cat. No.: HY-177344
CAS No.: 2857089-36-0
Research Areas:  

Cancer

IAJD-97 is a single-component ionizable amphiphilic Janus dendrimer carrier targeting mRNA delivery, which self-assembles into dendrimersomes (DNPs) via pH-responsive mechanisms to efficiently encapsulate and protect mRNA, while facilitating cellular uptake and endosomal escape through ionizable amine groups. IAJD-97 is promising for research of cancers .
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Cat. No.: HY-168940C
CAS No.: 139729-28-5
NH2-PEG10000-COOH is a compound composed of an NH2 group, PEG units (MW = 10000) and a carboxyl group (-COOH) . NH2-PEG-COOH is widely used for surface modification and functionalization of polymer carriers or nanoparticles .
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Cat. No.: HY-168940I
CAS No.: 139729-28-5
NH2-PEG20000-COOH is a compound composed of an NH2 group, PEG units (MW = 20000) and a carboxyl group (-COOH) . NH2-PEG-COOH is widely used for surface modification and functionalization of polymer carriers or nanoparticles .
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Cat. No.: HY-P11753A
IKVAVC acetate is a derivative peptide of IKVAV with an artificially added cysteine (Cys) at its C-terminus. IKVAVC acetate retains all the biological activities of the original IKVAV, mainly acting as a neural adhesion/differentiation signaling peptide, and is equipped with an engineered linker arm that enables covalent conjugation to molecular materials. IKVAV inhibits the migration and activation of fibroblasts, downregulates the TGF-β1 signaling pathway and endoplasmic reticulum stress, and promotes nerve repair. IKVAV regulates the phenotype of macrophages, shifting them from the pro-inflammatory M1 type to the pro-reparative M2 type .
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Cat. No.: HY-P11753
CAS No.: 1187540-64-2
IKVAVC is a derivative peptide of IKVAV with an artificially added cysteine (Cys) at its C-terminus. IKVAVC retains all the biological activities of the original IKVAV, mainly acting as a neural adhesion/differentiation signaling peptide, and is equipped with an engineered linker arm that enables covalent conjugation to molecular materials. IKVAV inhibits the migration and activation of fibroblasts, downregulates the TGF-β1 signaling pathway and endoplasmic reticulum stress, and promotes nerve repair. IKVAV regulates the phenotype of macrophages, shifting them from the pro-inflammatory M1 type to the pro-reparative M2 type .
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