PAMAM Dendrimer G0.0 amine (20% in methanol)
Based on 1 Customer Validation
PAMAM Dendrimer G0.0 amine is a pore-forming channel antagonist, including anthrax toxin protective antigen 63 (PA63, IC50 = 231 nM) and C. botulinum C2 toxin subunit (C2IIa, IC50 = 940 nM). At concentrations of 10 and 20 µM, PAMAM Dendrimer G0.0 amine reduces C2 toxin-induced death in HeLa cells. Additionally, PAMAM Dendrimer G0.0 amine is a chelator of nickel. In complexes with polysulfone membrane-bound chitosan, PAMAM Dendrimer G0.0 amine selectively captures and stores carbon dioxide (CO2) in a gas-feed system. PAMAM Dendrimer G0.0 amine has been used in the synthesis of PAMAM Dendrimer G0.5 Carboxylate (CAS 339334-01-9) and PAMAM Dendrimer G1.0 Amine (CAS 142986-44-5). PAMAM Dendrimer G0.0 amine can be used in research related to infections, cancer, and drug delivery systems.
For research use only. We do not sell to patients.
- CAS No.: 155773-72-1
- Formula: C22H48N10O4
- Molecular Weight:516.68
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 155773-72-1
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Appearance Liquid (Density: 1.162±0.06 g/cm3)
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Molecular Weight 516.68
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Formula C22H48N10O4
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Color Colorless to light yellow
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SMILES
O=C(CCN(CCN(CCC(NCCN)=O)CCC(NCCN)=O)CCC(NCCN)=O)NCCN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Heiden TC, et al. Developmental toxicity of low generation PAMAM dendrimers in zebrafish. Toxicol Appl Pharmacol. 2007 Nov 15;225(1):70-9. [Content Brief]
[2]. Förstner P, et al. Cationic PAMAM dendrimers as pore-blocking binary toxin inhibitors. Biomacromolecules. 2014 Jul 14;15(7):2461-74. [Content Brief]
[4]. Xiao Y, et al. Surface characterization, modification chemistry, and separation performance of polyimide and polyamidoamine dendrimer composite films. Langmuir. 2004 Sep 14;20(19):8230-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PAMAM Dendrimer G0.0 amine (20% in methanol) Related Classifications
HY-W157376 Related Classifications
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