339334-01-9
339334-01-9
Chemical Structure
PAMAM dendrimer G0.5 carboxylate sodium (8.78% w/w in water)
- CAS No.: 339334-01-9
- Formula:C46H72N10Na8O20
- Molecular Weight:1269.04
InChIKey: HLBBXYHSZWSLRS-UHFFFAOYSA-F
SMILES: O=C(CCN(CCC(O[Na])=O)CCNC(CCN(CCN(CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)=O)O[Na]
Biological Activity: PAMAM Dendrimer G0.5 Carboxylate sodium is a polyamidoamine (PAMAM) dendrimer with carboxylate termini. PAMAM Dendrimer G0.5 Carboxylate sodium conjugated with DACHPt is cytotoxic to A2780 ovarian cancer cells, MCF-7 breast cancer cells, Caco-2 colon cancer cells and BJ fibroblasts with IC50 values of 0.03, 1.6, 0.18 and 3 µM, respectively[1].
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PAMAM dendrimer G0.5 carboxylate sodium (8.78% w/w in water) | PAMAM Dendrimer G0.5 Carboxylate sodium is a polyamidoamine (PAMAM) dendrimer with carboxylate termini. PAMAM Dendrimer G0.5 Carboxylate sodium conjugated with DACHPt is cytotoxic to A2780 ovarian cancer cells, MCF-7 breast cancer cells, Caco-2 colon cancer cells and BJ fibroblasts with IC50 values of 0.03, 1.6, 0.18 and 3 µM, respectively. | |||||||||||||||||||||
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References
