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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
diseas
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "diseas" in MCE Product Catalog:
1
1 Cited Publications
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EZ-482, a novel ligand of apolipoprotein (apoE), binds to sites on apoE in the C-terminal domain with Kds of 5-10 μM for apoE3 and apoE4. EZ-482 binds to apoE4 by a unique N-terminal allosteric effect. EZ482 has the potential for Alzheimer’s diseas .
Cat. No.: HY-N16614
CAS No.: 1292294-31-5
Category:
Flavonoids Akebia quinata (Houttuyn) Decaisne Flavones Lardizabalaceae Terpenoids Sesquiterpenes Plants
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SPDV is a cleavable ADC linker used for diagnosis and treatment of cancer or B cell proliferative diseas.
Cat. No.: HY-177662A
CAS No.: 2273008-00-5
Synonyms: IONIS-TMPRSS6-Lrx sodium; ISIS 702843 sodium
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Sapablursen sodium, an antisense oligonucleotide, is designed to reduce the production of TMPRSS6 resulting in increased expression of hepcidin, which is the key regulator of iron homeostasis. Sapablursen sodium can be used in the research of blood diseas
Cat. No.: HY-129374
CAS No.: 1824718-79-7
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SPDH is a cleavable ADC linker used for diagnosis and treatment of cancer or B cell proliferative diseas.
Cat. No.: HY-148210
CAS No.: 1858204-23-5
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AMPK activator 9 (ZM-6) is a potent AMPK (α2β1γ1) activator with an EC50 value of 1.1 µM. AMPK activator 9 has the potential for the research of type 2 diabetes .
Cat. No.: HY-P11314
CAS No.: 241145-90-4
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Cat. No.: HY-103076R
CAS No.: 1016456-76-0
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EZ-482 (Standard) is the analytical standard of EZ-482 (HY-103076). This product is intended for research and analytical applications. EZ-482, a novel ligand of apolipoprotein (apoE), binds to sites on apoE in the C-terminal domain with Kds of 5-10 μM for apoE3 and apoE4. EZ-482 binds to apoE4 by a unique N-terminal allosteric effect. EZ482 has the potential for Alzheimer’s diseas .
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Imolamine is a potent antiplatelet aggregation agent, is a phenyl aminoxidiazole derivative. Imolamine has the potential for the research of coronary heart disease .
Cat. No.: HY-131570
CAS No.: 1997359-63-3
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JZ-4109 is a β-Glucocerebrosidase (GCase) modulator with an IC50 of 8 nM for wild-type recombinant GCase. JZ-4109 binds to an allosteric site at the GCase dimer interface, stabilizes wild-type and GCase N370S mutant GCase, induces GCase dimerization. JZ-4109 increases GCase protein abundance. JZ-4109 can be used for the research of Parkinson's diseas .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
