6 Results for "

fascioliasis

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "fascioliasis" in MCE Product Catalog:

1
Parishin B
Parishin B
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1 Cited Publications
Cat. No.: HY-N2124
CAS No.: 174972-79-3
Category:  

Gastrodia elata Bl. Orchidaceae Phenols Plants Disease Research Fields Cancer

Target:  

Reactive Oxygen Species (ROS) Ferroptosis Apoptosis

Parishin B is a multi-target biological agent with anti-epileptic, anti-fascioliasis and anti-breast cancer lung metastasis activities . Parishin B regulates the gene/protein activities of ACLY, unc13c, γ-aminobutynergic system, pro-inflammatory system, antioxidant system, monoaminergic system, ferroptosis-related pathways, as well as GST, CatL, Trx and TRIB3 . Parishin B modulates energy-lipid metabolism, synaptic function, neurotransmitter balance, neuroinflammation, oxidative stress, parasite detoxification/invasion processes, as well as apoptosis, cell cycle, proliferation and metastasis of cancer cells [1][2][3]. Parishin B can be used for related research of epilepsy, fascioliasis and breast cancer lung metastasis [3].
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Trimyristin
Trimyristin
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Cat. No.: HY-N2511
CAS No.: 555-45-3
Category:  

Metabolic Disease Myristicaceae Lipids Plants Myristica fragrans Houtt. Endogenous metabolite Disease Research Fields

Target:  

Cholinesterase (ChE) Phosphatase

Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity .
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Nitroxynil
Nitroxynil
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Cat. No.: HY-W049875
CAS No.: 1689-89-0
Target:  

Parasite ATP-binding cassette (ABC) transporters

Research Areas:  

Infection

Nitroxynil is a broad-spectrum veterinary anthelmintic and a substrate of ABCG2. Nitroxynil inhibits ATP production by uncoupling the oxidative phosphorylation process of mitochondria, thereby disrupting the parasite body covering, impairing its motility, and ultimately inducing parasite death. Nitroxynil induces chromosomal aberrations, sister chromatid exchanges and abnormal sperm morphology, and interferes with spermatogenesis. Nitroxynil is widely applicable to studies on fascioliasis, myiasis, Haemonchus spp. infections, and Oestrus ovis infections .
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Hexachloroparaxylene
Hexachloroparaxylene
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Cat. No.: HY-121154
CAS No.: 68-36-0
Synonyms: 1,4-Bis(trichloromethyl)benzene; Chloxyle
Target:  

Parasite

Research Areas:  

Infection Inflammation/Immunology

Hexachloroparaxylene could be used in the study of in fascioliasis in swine .
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Trimyristin (Standard)
Trimyristin (Standard)
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Cat. No.: HY-N2511R
CAS No.: 555-45-3
Category:  

Natural Products Microorganisms Myristicaceae Plants Myristica fragrans Houtt. Endogenous metabolite

Target:  

Reference Standards Cholinesterase (ChE) Phosphatase

Trimyristin (Standard) is the analytical standard of Trimyristin (HY-N2511). This product is intended for research and analytical applications. Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity .
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Trimyristin--d15
Trimyristin--d15
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Cat. No.: HY-N2511S
CAS No.: 1219804-94-0
Trimyristin--d15 is the d15-labeled Trimyristin (HY-N2511). Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity .
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