555-45-3
555-45-3
Chemical Structure
Trimyristin
- CAS No.: 555-45-3
- Formula:C45H86O6
- Molecular Weight:723.16
IUPAC Name: propane-1,2,3-triyl tritetradecanoate
InChIKey: DUXYWXYOBMKGIN-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCC(OC(COC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O
Biological Activity: Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Trimyristin | 99.72% | Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity. | ||||||||||||||||||||
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Trimyristin (Standard) | ≥98% | Trimyristin (Standard) is the analytical standard of Trimyristin (HY-N2511). This product is intended for research and analytical applications. Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity. | ||||||||||||||||||||
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Trimyristin--d15 | Trimyristin--d15 is the d15-labeled Trimyristin (HY-N2511). Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity. | |||||||||||||||||||||
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1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol | 1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol is a triacylglycerol containing palmitic acid (HY-N0830) at the sn-1 and sn-2 positions and octanoic acid (HY-41417) at the sn-3 position. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Octanoic acid is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoic acid is also a tremor-suppressing agent. | |||||||||||||||||||||
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1,2-Dimyristoyl-3-palmitoyl-rac-glycerol | 1,2-Dimyristoyl-3-palmitoyl-rac-glycerol (MMP) is a triacylglycerol that contains myristic acid and palmitic acid. | |||||||||||||||||||||
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1,2-Dipalmitoyl-3-decanoyl-rac-glycerol | 1,2-Dipalmitoyl-3-decanoyl-rac-glycerol (1,2-Palmitin-3-caprin), a compound mentioned in the chemical analysis of triglycerides and diacylglycerols in bovine milk fat, was identified by a specific chromatography-mass spectrometry technique, which is environmentally friendly and efficient. | |||||||||||||||||||||
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1,2-Palmitin-3-laurin | 1,2-Palmitin-3-laurin is an acylglycerol. | |||||||||||||||||||||
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1,3-Palmitin-2-caprin | 1,3-Palmitin-2-caprin is a fatty ester. | |||||||||||||||||||||
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1,3-Palmitin-2-laurin | 1,3-Palmitin-2-laurin is an acylglycerol. | |||||||||||||||||||||
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1,3-Myristin-2-laurin | 1,3-Myristin-2-laurin is an acylglycerol. | |||||||||||||||||||||
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1,3-Laurin-2-stearin | 1,3-Laurin-2-stearin is an acylglycerol. | |||||||||||||||||||||
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1,2-Laurin-3-stearin | 1,2-Laurin-3-stearin is an acylglycerol. | |||||||||||||||||||||
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2-Octanoyl-1,3-distearin-octanoic-1-13C | 2-Octanoyl-1,3-distearin-octanoic-1-13C is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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References
- [1]. Jaiswal P, et al. Enzyme Inhibition by Molluscicidal Components of Myristica fragrans Houtt. in the Nervous Tissue of Snail Lymnaea acuminata. Enzyme Res. 2010;2010:478746. [Content Brief]
- [2]. Akinlolu A, et al. Extraction, isolation and evaluation of anti-toxic principles from Moringa oleifera (MOF6) and Myristica fragrans (Trimyristin) upregulated Acetylcholinesterase concentrations in Sodium arsenite-induced neurotoxicity in rats[J]. Journal of Phytomedicine and Therapeutics, 2020, 19(2): 466-482.
