1219804-94-0
Chemical Structure
Trimyristin--d15
- CAS No.: 1219804-94-0
- Formula:C45H71D15O6
- Molecular Weight:738.25
IUPAC Name: 2-(palmitoyloxy)propane-1,3-diyl dipalmitate-1-13C
InChIKey: DUXYWXYOBMKGIN-NLBPYYKNSA-N
SMILES: [2H]C([2H])([2H])C([2H])([2H])CCCCCCCCCCCC(OC(COC(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])[2H])=O)COC(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])[2H])=O)=O
Biological Activity: Trimyristin--d15 is the d15-labeled Trimyristin (HY-N2511). Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity[1][2].
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Trimyristin--d15 | Trimyristin--d15 is the d15-labeled Trimyristin (HY-N2511). Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity. | |||||||||||||||||||||
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Trimyristin (Standard) | ≥98% | Trimyristin (Standard) is the analytical standard of Trimyristin (HY-N2511). This product is intended for research and analytical applications. Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity. | ||||||||||||||||||||
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Trimyristin | 99.72% | Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity. | ||||||||||||||||||||
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- [1]. Jaiswal P, et al. Enzyme Inhibition by Molluscicidal Components of Myristica fragrans Houtt. in the Nervous Tissue of Snail Lymnaea acuminata. Enzyme Res. 2010;2010:478746. [Content Brief]
- [2]. Akinlolu A, et al. Extraction, isolation and evaluation of anti-toxic principles from Moringa oleifera (MOF6) and Myristica fragrans (Trimyristin) upregulated Acetylcholinesterase concentrations in Sodium arsenite-induced neurotoxicity in rats[J]. Journal of Phytomedicine and Therapeutics, 2020, 19(2): 466-482.
