174972-79-3
Chemical Structure
Parishin B
- CAS No.: 174972-79-3
- Formula:C32H40O19
- Molecular Weight:728.65
IUPAC Name: 3-hydroxy-5-oxo-5-((4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzyl)oxy)-3-(((4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzyl)oxy)carbonyl)pentanoic acid
InChIKey: UNLDMOJTKKEMOG-IWOWLDPGSA-N
SMILES: O=C(OCC1=CC=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)C=C1)CC(O)(CC(O)=O)C(OCC3=CC=C(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)C=C3)=O
Biological Activity: Parishin B is a multi-target biological agent with anti-epileptic, anti-fascioliasis and anti-breast cancer lung metastasis activities[1][2][3]. Parishin B regulates the gene/protein activities of ACLY, unc13c, γ-aminobutynergic system, pro-inflammatory system, antioxidant system, monoaminergic system, ferroptosis-related pathways, as well as GST, CatL, Trx and TRIB3[1][2][3]. Parishin B modulates energy-lipid metabolism, synaptic function, neurotransmitter balance, neuroinflammation, oxidative stress, parasite detoxification/invasion processes, as well as apoptosis, cell cycle, proliferation and metastasis of cancer cells[1][2][3]. Parishin B can be used for related research of epilepsy, fascioliasis and breast cancer lung metastasis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Parishin B | 99.42% | Parishin B is a multi-target biological agent with anti-epileptic, anti-fascioliasis and anti-breast cancer lung metastasis activities. Parishin B regulates the gene/protein activities of ACLY, unc13c, γ-aminobutynergic system, pro-inflammatory system, antioxidant system, monoaminergic system, ferroptosis-related pathways, as well as GST, CatL, Trx and TRIB3. Parishin B modulates energy-lipid metabolism, synaptic function, neurotransmitter balance, neuroinflammation, oxidative stress, parasite detoxification/invasion processes, as well as apoptosis, cell cycle, proliferation and metastasis of cancer cells. Parishin B can be used for related research of epilepsy, fascioliasis and breast cancer lung metastasis. | ||||||||||||||||||||
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Parishin B (Standard) | 99.60% | Parishin B (Standard) is the analytical standard of Parishin B. This product is intended for research and analytical applications. Parishin B is a parishin metabolite that can be isolated from Gastrodia elata with antioxidant activity. | ||||||||||||||||||||
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References
- [1]. Sun M, et al. Parishin B Attenuates PTZ-Induced Seizures in Zebrafish and Is Associated with Neurotransmitter Balance and ACLY-Related Metabolic Pathways. Metabolites. 2026 Apr 18;16(4):275. [Content Brief]
- [2]. Zulqarnain M, et al. Integrated in vitro and in silico analysis of Artemisia absinthium identifies Parishin C and Parishin B as promising multitarget antifasciolic agents. Fitoterapia. 2026 Jan;188:107038. [Content Brief]
- [3]. Cheng X, et al. Parishin B blocking TRIB3-AKT1 interaction inhibits breast cancer lung metastasis. Frontiers in pharmacology. 2024;15:1517708. [Content Brief]
