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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
fluorine
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "fluorine" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: AV-45; Flobetapir
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Flobetapir (AV-45) may be a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18 .
1
1 Cited Publications
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DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. 18FDPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model .
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Tezacitabine is a cytostatic and cytotoxic antimetabolite and a nucleoside analogue. Tezacitabine irreversibly inhibits the ribonucleotide reductase and interferes with DNA replication and repair. Tezacitabine effectively induces cells apoptotic. Tezacitabine has the potential for leukemias and solid tumors (carcinomas) treatment .
Cat. No.: HY-45409
CAS No.: 146954-75-8
Synonyms: 2'-F-dU Phosphoramidite
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DMT-2’ Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) is a uridine phosphoramidite with a fluorine in the 2’ position. DMT-2’ Fluoro-dU Phosphoramidite could be used for nucleoside modification and synthesis of DNA .
Cat. No.: HY-400770
CAS No.: 1241391-14-9
Synonyms: 1-(2-Amino-4-fluoro-5-methylphenyl)-2-chloroethanone
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MC-GGFG-AM-(10Me-11F-Camptothecin) intermediate-1 (compound 19-2) is an intermediate for the synthesis of MC-GGFG-AM-(10Me-11F-Camptothecin) (HY-153360). Modifying groups can be added group. MC-GGFG-AM-(10Me-11F-Camptothecin) is a drug-linker conjugate used in the synthesis of ADCs .
Cat. No.: HY-W012725
CAS No.: 367-27-1
Cat. No.: HY-W008598
CAS No.: 403-29-2
Synonyms: p-Fluorophenacyl bromide
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2-Bromo-4'-fluoroacetophenone (p-Fluorophenacyl bromide) is a photoinducible DNA cleavage inducer.2-Bromo-4'-fluoroacetophenone generates fluorine-substituted phenyl radicals upon excitation and irradiation to cleave DNA, converting circular supercoiled DNA to circular relaxed and linear DNA forms.2-Bromo-4'-fluoroacetophenone exhibits concentration-dependent DNA cleaving activity.2-Bromo-4'-fluoroacetophenone can be used for the research of cancer .
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Altanserin can synthesize Fluorine-18 Altanserin. Fluorine-18 Altanserin binds to the brain 5HT2 receptors .
Cat. No.: HY-130723A
Purity: 99.65%
AMPK activator 2 (compound 7a) hydrochloride, a fluorine-containing proguanil derivative, up-regulates AMPK signal pathway and downregulates mTOR/4EBP1/p70S6K. AMPK activator 2 hydrochloride inhibits proliferation and migration of human cancer cell lines (UMUC3, T24, A549) .
Cat. No.: HY-76573
CAS No.: 1216897-16-3
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ML-10 is a small molecule apoptosis probe. Due to the presence of fluorine atoms, ML-10 can be radiolabeled with 18F isotopes and can be used for apoptosis positron emission tomography imaging studies. ML-10 is selectively taken up and accumulated in apoptotic cells, while being excluded from live or necrotic cells. In addition, the uptake of ML-10 is associated with apoptotic features such as caspase activation, Annexin-V binding, and disruption of mitochondrial membrane potential .
Cat. No.: HY-152203
CAS No.: 318498-81-6
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Mitochondrial respiration-IN-2 is the fluorine derivative of Virginiamycin M1 (HY-N6686). Mitochondrial respiration-IN-2 can inhibit mitochondrial translation of glioblastoma stem cells .
Cat. No.: HY-P11263
CAS No.: 1413933-25-1
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Cat. No.: HY-W850994
CAS No.: 93911-12-7
Synonyms: Tridecyl beta-D-maltopyranoside
Cat. No.: HY-101748
CAS No.: 62987-05-7
Synonyms: 40497S; FD 1
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Tegadifur is a fluorine-containing and anti-metabolic agent.
Cat. No.: HY-155869
CAS No.: 79671-09-3
Synonyms: 5-Fluoro-2′-deoxycytidine 5′-triphosphate
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5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
