1216897-16-3
Chemical Structure
ML-10
- CAS No.: 1216897-16-3
- Formula:C9H15FO4
- Molecular Weight:206.21
IUPAC Name: 2-(5-fluoropentyl)-2-methylmalonic acid
InChIKey: BOYGOAXVKOOCKN-UHFFFAOYSA-N
SMILES: O=C(O)C(C)(CCCCCF)C(O)=O
Biological Activity: ML-10 is a small molecule apoptosis probe. Due to the presence of fluorine atoms, ML-10 can be radiolabeled with 18F isotopes and can be used for apoptosis positron emission tomography imaging studies. ML-10 is selectively taken up and accumulated in apoptotic cells, while being excluded from live or necrotic cells. In addition, the uptake of ML-10 is associated with apoptotic features such as caspase activation, Annexin-V binding, and disruption of mitochondrial membrane potential[1].
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ML-10 | 95.0% | ML-10 is a small molecule apoptosis probe. Due to the presence of fluorine atoms, ML-10 can be radiolabeled with 18F isotopes and can be used for apoptosis positron emission tomography imaging studies. ML-10 is selectively taken up and accumulated in apoptotic cells, while being excluded from live or necrotic cells. In addition, the uptake of ML-10 is associated with apoptotic features such as caspase activation, Annexin-V binding, and disruption of mitochondrial membrane potential. | ||||||||||||||||||||
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