10 Results for "

hIgG

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "hIgG" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P990071
CAS No.: 2489584-93-0
Synonyms: LY-3016859
Fepixnebart (LY3016859) is a humanized monoclonal hIgG4 antibody, which binds and neutralizes only TGFα and epiregulin with high affinity. Fepixnebart can be used for the study of diabetic nephropathy and broad-spectrum chronic pain, including diabetic peripheral neuropathic pain (DPNP), signs and symptoms of osteoarthritis (OA), and chronic low back pain (CLBP) .
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Cat. No.: HY-P99445
CAS No.: 1450882-18-4
Synonyms: APG101; CAN008

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

Asunercept (APG101; CAN008) is a soluble CD95-Fc fusion protein (hIgG1) targeting CD95L. Asunercept disrupts CD95/CD95L signaling by selectively binding to CD95L. Asunercept can be used in the research of glioblastoma multiforme (GBM), myelodysplastic syndrome (MDS), and graft-versus-host disease (GvHD) .
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Cat. No.: HY-P99879
CAS No.: 2200269-79-8
Synonyms: Benegrastim; Bineuta; F 627

Target:  

STAT

Research Areas:  

Inflammation/Immunology

Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells .
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Cat. No.: HY-P990032
CAS No.: 2574438-65-4
Synonyms: EOS-448; EOS884448; GSK4428859A
Belrestotug (EOS-448) is an antagonistic anti-TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity. Belrestotug can be used for cancer and immunological research such as colon cancer .
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Cat. No.: HY-145775
CAS No.: 1425051-22-4
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

hIgG–hFc receptor-IN-1 (comp 66) is a human immunoglobulin G–human neonatal Fc receptor (hIgG–hFcRn) protein-protein interaction inhibitor, with an IC50 of 2 μM .
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Cat. No.: HY-P60128
CAS No.: 943235-73-2
Target:  

Peptides

Research Areas:  

Others

TTP is a generic surrogate peptide. TTP can be used for quantitative analysis of a recombinanthuman immunoglobulin G1 (hIgG1) in rat serum .
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Cat. No.: HY-187394
CAS No.: 1425050-80-1
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

hIgG-hFc receptor-IN-3 is a protein-protein interaction inhibitor of human immunoglobulin G-human neonatal Fc receptor (hIgG-hFcRn). Identified via virtual ligand screening and optimized through structure-activity relationship studies, hIgG-hFc receptor-IN-3 competitively inhibits the binding of IgG to FcRn, thereby accelerating the clearance of endogenous IgG. hIgG-hFc receptor-IN-3 can be used for the research of autoimmune diseases .
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Cat. No.: HY-187393
CAS No.: 1425051-06-4
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

hIgG-hFc receptor-IN-2 is a hFcRn inhibitor with an IC50 of 6 μM for human hFcRn. hIgG-hFc receptor-IN-2 blocks the protein-protein interaction between human IgG and the soluble extracellular domain of hFcRn. hIgG-hFc receptor-IN-2 serves as a tool for studying FcRn biology and a starting point for developing orally available small molecule hFcRn inhibitors. hIgG-hFc receptor-IN-2 can be used for the research of autoimmune disease .
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Cat. No.: HY-P11882
CAS No.: 947545-69-9
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

SYN1436 is a selective human neonatal Fc receptor (hFcRn) antagonist with an IC50 of 2.4 nM. SYN1436 binds to hFcRn and inhibits hFcRn-hIgG interaction. SYN1436 can be used for the research of autoimmune diseases .
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Cat. No.: HY-P991997

Target:  

Fc Receptor (FcR)

Research Areas:  

Others

Anti-CD16a Antibody (3G8) is a pan-CD16-specific antibody. Anti-CD16a Antibody (3G8) binds to an epitope overlapping with CD16a’s Fc binding site, inhibiting CD16a-IgG Fc region interactions.Anti-CD16a Antibody (3G8) recognizes CD16a, CD16b, and CD16b-NA1 and NA2 allelotypes expressed by neutrophils .
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