1425051-06-4
1425051-06-4
Chemical Structure
hIgG-hFc receptor-IN-2
- CAS No.: 1425051-06-4
- Formula:C26H29N5O2
- Molecular Weight:443.54
InChIKey: GGGWWDSRONFGRD-UHFFFAOYSA-N
SMILES: N#CC(C1=NC2=C(N=C1N3CCCCCCC3)C=CC=C2)C(NCC4=CC(OC)=CC=C4)=O
Biological Activity: hIgG-hFc receptor-IN-2 is a hFcRn inhibitor with an IC50 of 6 μM for human hFcRn. hIgG-hFc receptor-IN-2 blocks the protein-protein interaction between human IgG and the soluble extracellular domain of hFcRn. hIgG-hFc receptor-IN-2 serves as a tool for studying FcRn biology and a starting point for developing orally available small molecule hFcRn inhibitors. hIgG-hFc receptor-IN-2 can be used for the research of autoimmune disease[1].
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hIgG-hFc receptor-IN-2 | hIgG-hFc receptor-IN-2 is a hFcRn inhibitor with an IC50 of 6 μM for human hFcRn. hIgG-hFc receptor-IN-2 blocks the protein-protein interaction between human IgG and the soluble extracellular domain of hFcRn. hIgG-hFc receptor-IN-2 serves as a tool for studying FcRn biology and a starting point for developing orally available small molecule hFcRn inhibitors. hIgG-hFc receptor-IN-2 can be used for the research of autoimmune disease. | |||||||||||||||||||||
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