hIgG-hFc receptor-IN-3
hIgG-hFc receptor-IN-3 is a protein-protein interaction inhibitor of human immunoglobulin G-human neonatal Fc receptor (hIgG-hFcRn). Identified via virtual ligand screening and optimized through structure-activity relationship studies, hIgG-hFc receptor-IN-3 competitively inhibits the binding of IgG to FcRn, thereby accelerating the clearance of endogenous IgG. hIgG-hFc receptor-IN-3 can be used for the research of autoimmune diseases.
For research use only. We do not sell to patients.
- CAS No.: 1425050-80-1
- Formula: C25H27N5O2
- Molecular Weight:429.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
hIgG-hFc receptor-IN-3 is a quinoxaline-based small molecule, which is a novel FcRn antagonist obtained through structure-activity relationship (SAR) optimization of hit compounds identified via virtual ligand screening[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1425050-80-1
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Molecular Weight 429.51
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Formula C25H27N5O2
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SMILES
N#CC(C1=NC2=C(N=C1N3CCCCCC3)C=CC=C2)C(NCC4=CC(OC)=CC=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hIgG-hFc receptor-IN-3 Related Classifications
HY-187394 Related Classifications
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