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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
hPD-1
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "hPD-1" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-P81169A
Synonyms: Programmed cell death protein 1; CD279; CD279 antigen; hPD 1; hPD-1; hSLE1; PD 1; PD1; PDCD 1; PDCD1; PDCD1_HUMAN; Programmed cell death 1; Protein PD 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2.
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1 Cited Publications
Cat. No.: HY-P73344A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.;≥ 90%, as determined by HPLC.
Synonyms: CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2
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Cat. No.: HY-176763
CAS No.: 2376747-46-3
KZR-261 is a Sec61 translocase inhibitor. KZR-261 binds directly to the Sec61 channel, thereby inhibiting the biosynthesis of certain Sec61 substrate proteins, including oncogenic factors. KZR-261 activates the endoplasmic reticulum stress response. KZR-261 exhibits broad in vitro anticancer activity. KZR-261 shows antitumor efficacy in mouse models of cancer. KZR-261 can be used for the research of multiple myeloma, colorectal cancer, small cell lung cancer, pancreatic cancer, prostate cancer, non-Hodgkin's lymphoma, and mantle cell lymphoma [1].
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Bicyclopyrone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (Hpd) .
Cat. No.: HY-174830
CAS No.: 3099808-68-8
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GJ19 is a PD-L1 inhibitor with an IC50 of 32.06 nM. GJ19 can effectively bind to human/murine PD-L1 protein with Kd values of 171 and 290 nM, respectively. GJ19 concentration-dependently promotes HepG2 cell mortality in a co-culture model of HepG2/hPD-L1 and Jurkat T/hPD-1 cells. GJ19 effectively suppresses tumor growth in a B16-F10 melanoma mouse model. GJ19 can be used for the study of tumor immunotherapy [1].
Cat. No.: HY-P2478
CAS No.: 2815311-61-4
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Cat. No.: HY-P2474
CAS No.: 2135542-86-6
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Cat. No.: HY-P2477
CAS No.: 2135542-83-3
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Cat. No.: HY-P2478A
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Cat. No.: HY-135767R
CAS No.: 352010-68-5
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Bicyclopyrone (Standard) is the analytical standard of Bicyclopyrone. This product is intended for research and analytical applications. Bicyclopyrone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (Hpd) .
Cat. No.: HY-184989
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PD-L1-IN-12 is an orally active and potent selenium-containing small-molecule PD-L1 inhibitor (KD = 9.06 nM). PD-L1-IN-12 can mediate the internalization of PD-L1 and strongly block hPD-1 and hPD-L1 interaction (IC50 = 5.2 nM). PD-L1-IN-12 can be used in colorectal cancer immunology research [1].
Cat. No.: HY-163837
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PD-1/PD-L1-IN-48 (compound HD10) is a potent inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.1 nM. PD-1/PD-L1-IN-48 plays an important role in cancer research [1].
Cat. No.: HY-P705070
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Programmed cell death protein 1; hPD-1; PDCD1; CD279
Cat. No.: HY-P73342A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2
Cat. No.: HY-P704840
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Programmed cell death protein 1; PDCD1; PD-1; hPD-1; CD279
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
