PD-1/PD-L1-IN-48
PD-1/PD-L1-IN-48 (compound HD10) is a potent inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.1 nM. PD-1/PD-L1-IN-48 plays an important role in cancer research.
For research use only. We do not sell to patients.
- Formula: C32H29F2N3O5
- Molecular Weight:573.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MC-38 | IC50 |
>8 μM
Compound: HD10
|
Antiproliferative activity against mouse MC38 cells expressing hPD-L1 incubated for 48 hrs by CCK8 assay
Antiproliferative activity against mouse MC38 cells expressing hPD-L1 incubated for 48 hrs by CCK8 assay
|
[PMID: 39032403] |
Chemical Information
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Molecular Weight 573.59
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Formula C32H29F2N3O5
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SMILES
N#CC1=CN=CC(COC2=CC(OCC3=C(C(C4=CC5=C(OCCO5)C=C4)=CC=C3)C(F)F)=CC=C2CNCCO)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)