16 Results for "

human B7-H3

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "human B7-H3" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P9966
CAS No.: 1353485-38-7
Synonyms: MGA271

Target:  

CD276/B7-H3

Research Areas:  

Cancer

Enoblituzumab (MGA271) is a humanized IgG1κ monoclonal antibody recognizing human B7-H3 protein, a member of the B7 family of immune regulators .
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Cat. No.: HY-P99367
CAS No.: 2484870-90-6
Synonyms: DS-7300a Antibody; MABX-9001A Antibody

Target:  

CD276/B7-H3

Research Areas:  

Inflammation/Immunology Cancer

Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur .
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Cat. No.: HY-148837
CAS No.: 2883535-99-5
GT19630 is an orally active c-Myc PROTAC targeted degrader based on the cereblon E3 ubiquitin ligase, with an IC50 of 1.5 nM against human c-Myc. GT19630 mediates the degradation of MYC, GSPT1, GSPT2, CK1 alpha, N-Myc, B7-H3 and XIAP, and disrupts the MYC-GSPT1 synergistic regulatory feedback loop. GT19630 inhibits cell proliferation, blocks S-phase progression of the cell cycle, promotes cell apoptosis, reduces cell migration capacity, induces integrated stress response, and blocks oxidative phosphorylation by inhibiting the TCA cycle. GT19630 can be used in the research of Myc-driven hematological cancers, small cell lung cancer, breast cancer, TP53-mutant cancers, and venetoclax-resistant cancers .
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Cat. No.: HY-P990340

Target:  

CD276/B7-H3

Research Areas:  

Inflammation/Immunology

Anti-B7-H3/CD276 Antibody is a CHO-expressed human antibody targeting B7-H3/CD276. Anti-B7-H3/CD276 Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-B7-H3/CD276 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P992347

Target:  

CD276/B7-H3

Research Areas:  

Cancer

DS-5573a is a human monoclonal antibody targeting B7-H3, with a Kd of 1.8 nM for the 4Ig isoform and 11 nM for the 2Ig isoform. DS-5573a induces antibody-dependent cellular cytotoxicity and antibody-dependent cellular phagocytosis against B7-H3-expressing cancer cells. DS-5573a exerts dose-dependent anti-tumor activity via effector cells. DS-5573a can be used in the research of cancers including breast adenocarcinoma, non-small cell lung cancer, renal cell adenocarcinoma, gastric cancer and prostate cancer .
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Cat. No.: HY-P7326
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4Ig-B7-H3; B7H3
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Cat. No.: HY-P7327
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4Ig-B7-H3; B7H3
Species:  
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Cat. No.: HY-P78930
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4Ig-B7-H3; B7H3
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Cat. No.: HY-P70652
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4Ig-B7-H3; B7H3
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Cat. No.: HY-P74317
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4Ig-B7-H3; B7H3
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Cat. No.: HY-P77538
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4Ig-B7-H3; B7H3
Species:  
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Cat. No.: HY-P700880
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4Ig-B7-H3; B7H3
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Cat. No.: HY-P78074
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4Ig-B7-H3; B7H3
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Cat. No.: HY-P701302
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4Ig-B7-H3; B7H3
Species:  
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Cat. No.: HY-P704456
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4Ig-B7-H3; B7H3
Species:  
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Cat. No.: HY-P700448
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4Ig-B7-H3; B7H3
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