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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
human WDR5
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "human WDR5" in MCE Product Catalog:
Cat. No.: HY-RS15785
Target:
Research Areas:
WDR5 Human Pre-designed siRNA Set A contains three designed siRNAs for WDR5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-150400A
CAS No.: 2694057-55-9
Synonyms: MS132N TFA
XF056-132 (MS132N TFA) is an inactive WDR5 PROTAC degrader with a Kd value of 106 nM against human targets, and exhibits no significant binding to the VHL complex, serves as a negative control for MS132. XF056-132 binds to WDR5, does not induce WDR5 degradation in pancreatic cancer cells, and exerts no inhibitory effect on adenocarcinoma cells. XF056-132 can be used in the research of pancreatic ductal adenocarcinoma .
Cat. No.: HY-150400
CAS No.: 2407450-73-9
Synonyms: MS132N
XF056-132 free base (MS132N) is an inactive WDR5 PROTAC degrader with a Kd value of 106 nM against human targets, and exhibits no significant binding to the VHL complex, serves as a negative control for MS132. XF056-132 free base binds to WDR5, does not induce WDR5 degradation in pancreatic cancer cells, and exerts no inhibitory effect on adenocarcinoma cells. XF056-132 free base can be used in the research of pancreatic ductal adenocarcinoma .
Cat. No.: HY-RS15789
Target:
Research Areas:
WDR5B Human Pre-designed siRNA Set A contains three designed siRNAs for WDR5B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-168487
CAS No.: 2737222-94-3
PROTAC WDR5 degrader 1 is a heterobifunctional WDR5 PROTAC degrader with a DC50 value of 53 nM and a Kd value of 18 nM, exhibiting selective WDR5 degradation activity and cell permeability. PROTAC WDR5 degrader 1 induces proliferation defects in leukemia cells, with enhanced efficacy in cells overexpressing VHL. PROTAC WDR5 degrader 1 is applicable to research related to acute myeloid leukemia .
Cat. No.: HY-P703615
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: WDR5; WD Repeat Domain 5; CFAP89; BIG‑3; SWD3; Cilia And Flagella Associated Protein 89; WD Repeat‑Containing Protein 5; BMP2‑Induced 3‑Kb Gene Protein; BMP‑2‑Induced Gene 3 Kb; BIG3; SWD3, Set1c WD40 Repeat Protein, Homolog (S. Cerevisiae); SWD3, Set1c W
Cat. No.: HY-P702880
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDR5; WD Repeat Domain 5; CFAP89; BIG‑3; SWD3; Cilia And Flagella Associated Protein 89; WD Repeat‑Containing Protein 5; BMP2‑Induced 3‑Kb Gene Protein; BMP‑2‑Induced Gene 3 Kb; BIG3; SWD3, Set1c WD40 Repeat Protein, Homolog (S. Cerevisiae); SWD3, Set1c W
Species:
Source:
Cat. No.: HY-P702881
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDR5; WD Repeat Domain 5; CFAP89; BIG‑3; SWD3; Cilia And Flagella Associated Protein 89; WD Repeat‑Containing Protein 5; BMP2‑Induced 3‑Kb Gene Protein; BMP‑2‑Induced Gene 3 Kb; BIG3; SWD3, Set1c WD40 Repeat Protein, Homolog (S. Cerevisiae); SWD3, Set1c W
Species:
Source:
Target:
Cat. No.: HY-180690A
CAS No.: 3069873-81-7
Synonyms: Imidazolepyruvic acid TFA
Target:
Cat. No.: HY-P702887
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KMT2C; Homologous To ALR Protein; Prev. MLL3; Myeloid/Lymphoid Or Mixed-Lineage Leukemia 3; Histone-Lysine N-Methyltransferase 2C; [Histone H3]-Lysine(4) N-Methyltransferase; HALR; Histone-Lysine N-Methyltransferase MLL3; KIAA1506; Lysine N-Methyltransfer
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
