Imidazole-4-pyruvic acid TFA
Imidazole-4-pyruvic acid TFA (Imidazolepyruvic acid TFA) is a metabolic precursor for histidine synthesis and selective stable isotope labeling of histidine residues. Imidazole-4-pyruvic acid TFA serves as a precursor for selective histidine labeling in overexpressed proteins of Escherichia coli. Imidazole-4-pyruvic acid TFA can be used in studies related to cancer and fungal mold infections.
For research use only. We do not sell to patients.
- Purity: 96.20%
- CAS No.: 3069873-81-7
- Formula: C8H7F3N2O5
- Molecular Weight:268.15
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Imidazole-4-pyruvic acid (50-200 mg/L) TFA achieves >80% 13C histidine labeling efficiency in overexpressed α-synuclein at a concentration of 50 mg/L, with efficiency approaching maximum at higher concentrations[1].
Imidazole-4-pyruvic acid TFA enables highly selective backbone 13C labeling of histidine residues in overexpressed H6-GB1 protein, with no cross-labeling of other residues[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3069873-81-7
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Appearance Solid
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Molecular Weight 268.15
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Formula C8H7F3N2O5
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Color White to off-white
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SMILES
O=C(C(CC1=CN=CN1)=O)O.OC(C(F)(F)F)=O
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Synonyms
Imidazolepyruvic acid TFA
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
DMSO : 16.67 mg/mL (62.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (286 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7293 mL | 18.6463 mL | 37.2926 mL | 93.2314 mL |
| 5 mM | 0.7459 mL | 3.7293 mL | 7.4585 mL | 18.6463 mL | |
| 10 mM | 0.3729 mL | 1.8646 mL | 3.7293 mL | 9.3231 mL | |
| 15 mM | 0.2486 mL | 1.2431 mL | 2.4862 mL | 6.2154 mL | |
| 20 mM | 0.1865 mL | 0.9323 mL | 1.8646 mL | 4.6616 mL | |
| 25 mM | 0.1492 mL | 0.7459 mL | 1.4917 mL | 3.7293 mL | |
| 30 mM | 0.1243 mL | 0.6215 mL | 1.2431 mL | 3.1077 mL | |
| 40 mM | 0.0932 mL | 0.4662 mL | 0.9323 mL | 2.3308 mL | |
| 50 mM | 0.0746 mL | 0.3729 mL | 0.7459 mL | 1.8646 mL | |
| 60 mM | 0.0622 mL | 0.3108 mL | 0.6215 mL | 1.5539 mL |
Imidazole-4-pyruvic acid TFA Related Classifications
HY-180690A Related Classifications
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