32 Results for "

il-2r-alpha

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "il-2r-alpha" in MCE Product Catalog:

Cat. No.: HY-P99410
CAS No.: 879293-15-9
Synonyms: AMG 714; PRV-015

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ordesekimab (AMG 714; PRV-015) is a fully human IgG1κ anti-IL-15 (Interleukin Related) monoclonal antibody. The binding of Ordesekimab to IL-15 inhibits the interaction of IL-15 with the IL-2Rβ and common γ chain of the IL-15 receptor complex, but not with the IL-15Rα chain. Ordesekimab has the potential for study of nonresponsive celiac disease (NRCD) .
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Cat. No.: HY-108738
CAS No.: 152923-56-3
Purity:  99.18%
Synonyms: Ro 24-7375
Daclizumab (Ro 24-7375) is a humanized, monoclonal antibody that blocks CD25 (α-subunit of the high-affinity interleukin-2 receptor (IL-2R-HA)). Daclizumab inhibits effector T cell activation, regulatory T cell (Treg) expansion and survival, and activation-induced T-cell apoptosis. Daclizumab increases IL-2 bioavailability to bind to the intermediate-affinity IL-2R (IL-2R-IA), driving the expansion of anti-inflammatory CD56bright natural killer (NK) cells. Daclizumab can be used for multiple sclerosis and cancer research .
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Cat. No.: HY-P990281

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) is a rat-derived IgG1 λ type antibody inhibitor, targeting to mouse CD25/IL-2Rα. Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) can deplete CD25+ T cells. Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) can be used for the researches of immunology and inflammation, such as atopic dermatitis .
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Cat. No.: HY-P99902
CAS No.: 1776942-10-9
Synonyms: FAP-il2v; RO6874281; RG7461

Target:  

Interleukin Related

Research Areas:  

Cancer

Simlukafusp alfa (FAP-IL2v) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAPα) and an IL-2 variant that only binds IL-2Rβγ. Isotype: human IgG1 .
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Cat. No.: HY-P991740

Research Areas:  

Cancer

IBI-363 is a PD-1/IL-2 bispecific antibody with functions of blocking the PD-1/PD-L1 pathway and activating the IL-2 pathway. The IL-2 arm of IBI-363 retains affinity for IL-2Rα but attenuates binding ability to IL-2Rβ and IL-2Rγ to reduce toxicity. The PD-1 binding arm of IBI-363 enables PD-1 blockade and selective delivery of IL-2. IBI-363 can be used in cancer research, such as non-small cell lung cancer .
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Cat. No.: HY-119424
CAS No.: 515846-21-6
Purity:  98.11%
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

SP4206 is an IL-2/IL-2Rα interaction inhibitor. SP4206 binds with high affinity (Kd=70 nM) to IL-2 and blocks binding to its natural receptor IL-2Rα (Kd=10 nM) .
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Cat. No.: HY-P1453A
Research Areas:  

Cancer

CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development .
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Cat. No.: HY-121743
CAS No.: 193744-04-6
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ro26-4550 is a low micromolar antagonist of IL-2/IL-2Rα binding with an IC50 value of 3 μM .
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Cat. No.: HY-P1453
Research Areas:  

Cancer

CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development .
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Cat. No.: HY-P99664
CAS No.: 152981-31-2

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Inolimomab is an anti-interleukin-2 receptor (IL-2R) α chain monoclonal antibody. Inolimomab improves the survival rate in the early research of treating acute graft-versus-host disease (aGVHD) .
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Cat. No.: HY-P990866

Target:  

Interleukin Related

Research Areas:  

Cancer

Anti-CD25/IL-2Rα Antibody (7G7B6) is an anti-human CD25/IL-2Rα IgG2a monoclonal antibody. Anti-CD25/IL-2Rα Antibody (7G7B6) can inhibit the growth of tumors. Anti-CD25/IL-2Rα Antibody (7G7B6) can be used for research on leukemia. The recommend isotype control of Anti-CD25/IL-2Rα Antibody (7G7B6): Mouse IgG2a kappa, Isotype Control (HY-P99978) .
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Cat. No.: HY-103390
CAS No.: 1217448-66-2
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ro26-4550 TFA is a low micromolar antagonist of IL-2/IL-2Rα binding with an IC50 value of 3 μM .
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Cat. No.: HY-P74809
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: il2rA; TAC Antigen; Prev. IDDM10; Insulin-Dependent Diabetes Mellitus 10; Prev. il2r; CD25 Antigen; Interleukin-2 Receptor Subunit alpha; il-2-RA; CD25; il2-RA; Interleukin 2 Receptor, alpha; IMD41; il-2 Receptor Subunit alpha; TCGFR; il-2r Subunit alpha
Species:  
Rat
Source:  
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Cat. No.: HY-P74811
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: il2rA; TAC Antigen; Prev. IDDM10; Insulin-Dependent Diabetes Mellitus 10; Prev. il2r; CD25 Antigen; Interleukin-2 Receptor Subunit alpha; il-2-RA; CD25; il2-RA; Interleukin 2 Receptor, alpha; IMD41; il-2 Receptor Subunit alpha; TCGFR; il-2r Subunit alpha
Species:  
Source:  
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Cat. No.: HY-P76785
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: il2rA; TAC Antigen; Prev. IDDM10; Insulin-Dependent Diabetes Mellitus 10; Prev. il2r; CD25 Antigen; Interleukin-2 Receptor Subunit alpha; il-2-RA; CD25; il2-RA; Interleukin 2 Receptor, alpha; IMD41; il-2 Receptor Subunit alpha; TCGFR; il-2r Subunit alpha
Species:  
Source:  
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Cat. No.: HY-P76786
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: il2rA; TAC Antigen; Prev. IDDM10; Insulin-Dependent Diabetes Mellitus 10; Prev. il2r; CD25 Antigen; Interleukin-2 Receptor Subunit alpha; il-2-RA; CD25; il2-RA; Interleukin 2 Receptor, alpha; IMD41; il-2 Receptor Subunit alpha; TCGFR; il-2r Subunit alpha
Species:  
Source:  
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Cat. No.: HY-P76787
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: il2rA; TAC Antigen; Prev. IDDM10; Insulin-Dependent Diabetes Mellitus 10; Prev. il2r; CD25 Antigen; Interleukin-2 Receptor Subunit alpha; il-2-RA; CD25; il2-RA; Interleukin 2 Receptor, alpha; IMD41; il-2 Receptor Subunit alpha; TCGFR; il-2r Subunit alpha
Species:  
Source:  
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Cat. No.: HY-P78412
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: il2rA; TAC Antigen; Prev. IDDM10; Insulin-Dependent Diabetes Mellitus 10; Prev. il2r; CD25 Antigen; Interleukin-2 Receptor Subunit alpha; il-2-RA; CD25; il2-RA; Interleukin 2 Receptor, alpha; IMD41; il-2 Receptor Subunit alpha; TCGFR; il-2r Subunit alpha
Species:  
Source:  
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Cat. No.: HY-P72550
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: il2rA; TAC Antigen; Prev. IDDM10; Insulin-Dependent Diabetes Mellitus 10; Prev. il2r; CD25 Antigen; Interleukin-2 Receptor Subunit alpha; il-2-RA; CD25; il2-RA; Interleukin 2 Receptor, alpha; IMD41; il-2 Receptor Subunit alpha; TCGFR; il-2r Subunit alpha
Species:  
Source:  
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Cat. No.: HY-P75629
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: il2rA; TAC Antigen; Prev. IDDM10; Insulin-Dependent Diabetes Mellitus 10; Prev. il2r; CD25 Antigen; Interleukin-2 Receptor Subunit alpha; il-2-RA; CD25; il2-RA; Interleukin 2 Receptor, alpha; IMD41; il-2 Receptor Subunit alpha; TCGFR; il-2r Subunit alpha
Species:  
Source:  
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