2. Search Result
Search Result
Pathways Recommended: Cell Cycle/DNA Damage
Results for "

intramolecular cyclization

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Fluorescent Dye

1

Peptides

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125372
    2-Amino benzamidoxime

    ABAO

    		 Biochemical Assay Reagents Others
    2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n
    2-Amino benzamidoxime
  • HY-133157
    FAICAR

    5-Formamidoimidazole-4-carboxamide ribotide

    		 DNA/RNA Synthesis Infection
    FAICAR (5-Formamidoimidazole-4-carboxamide ribotide) is a purine nucleotide and the IMP cyclohydrolase substrate of Cryptococcus neoformans ATIC. It is a key intermediate in the de novo purine synthesis pathway. FAICAR can be used in studies related to Cryptococcus neoformans infection .
    FAICAR
  • HY-34611
    Boc-L-2,4-Diaminobutyric acid

    N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH

    		 Drug Intermediate ASCT Neurological Disease Cancer
    Boc-L-2,4-Diaminobutyric acid (N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH) is a versatile synthetic starting material with a cleavable protecting group. Boc-L-2,4-Diaminobutyric acid not only reduces the backbone cleavage rate by protecting the side-chain γ-amino group, but also triggers intramolecular cyclization of self-immolative linkers under acidic cleavage conditions, thus constructing stimuli-responsive materials. Boc-L-2,4-Diaminobutyric acid is also an important building block for bioactive molecules. It can be used in the synthesis of ASCT2 (SLC1A5) inhibitors and carboxynorspermine, and can also serve as an internal standard to support the quantitative detection of specific intracellular amino acids by UPLC-QQQ-MS .
    Boc-L-2,4-Diaminobutyric acid
  • HY-121564
    Radermachol

    		Fluorescent Dye Others
    Radermachol is a red pigment that can be synthesized in four steps via a key ytterbium triflate-catalyzed furan cyclization and intramolecular nucleophilic acylation reaction .
    Radermachol
  • HY-177482
    Pro-PTX

    		Drug Intermediate Cancer
    Pro-PTX is a Pd-sensitive Paclitaxel (HY-B0015) prodrug with anticancer activity 200 to 700-fold lower than that of the parent compound. Pro-PTX triggers intramolecular cyclization via Pd-catalyzed depropargylation to release active Paclitaxel (HY-B0015) and a non-toxic byproduct. Pro-PTX diffuses efficiently through porous agarose and alginate hydrogel networks, reacts with embedded Pd nanosheets and gets activated. Pro-PTX exhibits significantly reduced cytotoxicity and antiproliferative activity in cancer cells and non-cancerous human cerebrovascular pericytes. Pro-PTX is applicable for research related to non-small cell lung cancer, glioblastoma and lung cancer .
    Pro-PTX
  • HY-W392267
    α-Methylcinnamyl alcohol

    		Drug Derivative Others
    α-Methylcinnamyl alcohol is a derivative of Cinnamyl Alcohol (HY-Y0078) .
    α-Methylcinnamyl alcohol
  • HY-D3191
    L&M-D-MR

    		Fluorescent Dye Aminopeptidase Monoamine Oxidase Infection Metabolic Disease
    L&M-D-MR is a highly specific fluorescent "AND" logic probe with response moieties for leucine aminopeptidase (LAP) and monoamine oxidase (MAO). The coexistence of both LAP and MAO is required for L&M-D-MR to trigger intramolecular cyclization, release fluorophores and activate fluorescence. In the presence of only a single enzyme, L&M-D-MR generates only an extremely weak signal. L&M-D-MR enables bioimaging in living cells and mouse models, and can effectively distinguish different subtypes of liver diseases via blood samples or test strips. L&M-D-MR is widely used in studies related to liver cirrhosis, hepatitis B and drug-induced liver injury .
    L&M-D-MR

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: