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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
intramolecular cyclization
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "intramolecular cyclization" in MCE Product Catalog:
Synonyms: ABAO
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2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n
Synonyms: 5-Formamidoimidazole-4-carboxamide ribotide
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Cat. No.: HY-E70421
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Peptide ligase is an Asx-specific asparaginyl endopeptidase (AEP) ligase and cyclase that can be isolated from the pods of butterfly pea (Clitoria ternatea). Peptide ligase mediates traceless intramolecular cyclization of polypeptides. Peptide ligase mediates intermolecular ligation of polypeptides or proteins. Peptide ligase can be used to cyclize food-derived angiotensin-converting enzyme (ACE) inhibitory peptides, thereby enhancing the stability and biological activity of ACE inhibitory peptides. Peptide ligase is applicable to relevant research in the fields of food and biopharmaceuticals .
Cat. No.: HY-34611
CAS No.: 25691-37-6
Synonyms: N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH
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Cat. No.: HY-156249
CAS No.: 1466546-45-1
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NMS-P528 is a DNA minor groove alkylating agent and ADC payload. NMS-P528 undergoes intramolecular cyclization to form reactive electrophilic derivatives, which in turn induce DNA damage, cell cycle arrest, and Apoptosis. NMS-P528 shows no significant anti-tumor activity as a free payload in a HER2-negative Raji lymphoma mouse xenograft model. NMS-P528 serves as the cytotoxic payload for the antibody-drug conjugate EV20/NMS-P945. NMS-P528 can be used in research related to breast cancer, gastric cancer, colon adenocarcinoma, Burkitt's lymphoma, neuroblastoma, pancreatic cancer, prostate cancer, head and neck cancer, ovarian cancer, and melanoma .
Cat. No.: HY-121564
CAS No.: 95378-00-0
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Cat. No.: HY-177482
CAS No.: 3011748-20-9
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Pro-PTX is a Pd-sensitive Paclitaxel (HY-B0015) prodrug with anticancer activity. Pro-PTX triggers intramolecular cyclization via Pd-catalyzed depropargylation to release active Paclitaxel (HY-B0015) and a non-toxic byproduct. Pro-PTX exhibits low cytotoxicity and antiproliferative activity in cancer cells and non-cancerous human cerebrovascular pericytes. Pro-PTX is applicable for research related to non-small cell lung cancer, glioblastoma and lung cancer .
Cat. No.: HY-E71593
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2-Methylfumaryl-CoA isomerase (EC 5.4.1.3), purified from the bacterium Chloroflexus aurantiacus, acts as an intramolecular CoA transferase and does not transfer CoA to free mesaconate, and is part of the 3-hydroxypropanoate cycle for carbon assimilation.
Cat. No.: HY-W753582A
CAS No.: 905832-10-2
Synonyms: 1-Me-AZADOL
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1-Methyl-2-azaadamantan-2-ol (1-Me-AZADOL) is a functional analog of the nitroxyl radical 1-Me-AZADO (HY-W753582) .
Cat. No.: HY-W392267
CAS No.: 1504-55-8
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α-Methylcinnamyl alcohol is a derivative of Cinnamyl Alcohol (HY-Y0078) .
Cat. No.: HY-D3191
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
