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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
invariant chain
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "invariant chain" in MCE Product Catalog:
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Human Cathepsin S (CTSS) is a cysteine protease with elastinolytic activity. Human Cathepsin S is inhibited by cysteine protease inhibitors such as E-64 (HY-15282) and cystatin C. Human Cathepsin S cleaves substrates including elastin, TGF-β1, Myelin basic protein (HY-P1821), PAR2, SIRT1, collagen 18A1, FKN, and MHC-II invariant chain fragments, thereby driving processes such as elastic matrix degradation, TGF-β1 signaling, demyelination, PAR2-mediated calcium mobilization, NF-κB activation, hepatic fibrosis, immune homeostasis regulation, and antigen presentation. Human Cathepsin S can be used in the research of cardiovascular diseases, chronic kidney diseases, autoimmune diseases, tumors, Alzheimer's disease, and obesity .
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1 Cited Publications
Cat. No.: HY-P85898
Synonyms: CD 74 antibody; CD74 antibody; CD74 antigen; invariant polypeptide of major histocompatibility complex; class II antigen-associated; antibody; CD74 antigen antibody; CD74 molecule antibody; CD74 molecule; major histocompatibility complex; class II invariant chain antibody; CLIP antibody; DHLAG antibody; Gamma chain of class II antigens antibody; HG2A_HUMAN antibody; HLA class II histocompatibility antigen gamma chain antibody; HLA DR antigens associated invariant chain antibody; HLA DR gamma antibody; HLA-DR antigens-associated invariant chain antibody; HLA-DR-gamma antibody; HLADG antibody; HLADR antigens associated invariant chain antibody; Ia antigen associated invariant chain antibody; Ia antigen-associated invariant chain antibody; Ia associated invariant chain antibody; Ia gamma antibody; Ii antibody; invariant polypeptide of major histocompatibility complex class II antigen associated antibody; la-gamma antibody; Major histocompatibility complex class II invariant chain antibody; MHC HLA DR gamma chain antibody; MHC HLA-DR gamma chain antibody; p33 antibody; p35 antibody; Protein 41 antibody;
Cat. No.: HY-P1826
CAS No.: 648881-58-7
Target:
Research Areas:
Cat. No.: HY-123531
CAS No.: 400797-24-2
Target:
Research Areas:
JNJ 10329670 is a potent and selective noncovalent cathepsin S inhibitor with a Ki value of 34 nM for human cathepsin S. JNJ 10329670 blocks invariant chain proteolysis in B cells and dendritic cells, as well as antigen-induced T cell proliferation .
Cat. No.: HY-P1826A
Target:
Research Areas:
Cat. No.: HY-P81537A
Synonyms: CD74; DHLAG; HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD74
Cat. No.: HY-P72931
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD74; Ia-Associated invariant chain; Prev. DHLAG; HLA-DR-Gamma; CLIP; Ia Antigen-Associated invariant chain; CD74 Antigen (invariant Polypeptide Of Major Histocompatibility Complex, Class II Antigen-Associated); CD74 Antigen; CD74 Molecule, Major Histocom
Cat. No.: HY-P705402
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD74; Ia-Associated invariant chain; Prev. DHLAG; HLA-DR-Gamma; CLIP; Ia Antigen-Associated invariant chain; CD74 Antigen (invariant Polypeptide Of Major Histocompatibility Complex, Class II Antigen-Associated); CD74 Antigen; CD74 Molecule, Major Histocom
Cat. No.: HY-P72710
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD74; Ia-Associated invariant chain; Prev. DHLAG; HLA-DR-Gamma; CLIP; Ia Antigen-Associated invariant chain; CD74 Antigen (invariant Polypeptide Of Major Histocompatibility Complex, Class II Antigen-Associated); CD74 Antigen; CD74 Molecule, Major Histocom
Cat. No.: HY-P78262
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD74; Ia-Associated invariant chain; Prev. DHLAG; HLA-DR-Gamma; CLIP; Ia Antigen-Associated invariant chain; CD74 Antigen (invariant Polypeptide Of Major Histocompatibility Complex, Class II Antigen-Associated); CD74 Antigen; CD74 Molecule, Major Histocom
Cat. No.: HY-P72609
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGKC; Ig Kappa chain C Region TI; Immunoglobulin Kappa Constant; Ig Kappa chain C Region OU; HCAK1; Ig Kappa chain C Region EU; Immunoglobulin Kappa (invariant Region); Ig Kappa chain C Region AG; Immunoglobulin Kappa Light chain (VJ); Ig Kappa chain C Re
Cat. No.: HY-186103
CAS No.: 1204401-08-0
Research Areas:
Glycolipid C34, α-GalCer (HY-102022) analog, is a CD1d-binding glycolipid antinfection agent. Glycolipid C34 mediates invariant natural killer T cell activation and increases the secretion of IFN-γ and IL-4. Glycolipid C34 promotes clearance of bacterial infections in murine models and enhances protective immunity against viral infections. Glycolipid C34 can be used for the research of bacterial infection, viral infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
