![[Ir(cod)Cl]2](https://file.medchemexpress.com/product_pic/hy-w008260.gif "Click to View [Ir(cod)Cl]2 Product Detail")
![[IrCl(COE)2]2](https://file.medchemexpress.com/product_pic/hy-w020887.gif "Click to View [IrCl(COE)2]2 Product Detail")
![Ir[p-F(t-Bu)-ppy]3](https://file.medchemexpress.com/product_pic/hy-w035599.gif "Click to View Ir[p-F(t-Bu)-ppy]3 Product Detail")
![[Ir(ppy)2(bpy)]PF6](https://file.medchemexpress.com/product_pic/hy-w072530.gif "Click to View [Ir(ppy)2(bpy)]PF6 Product Detail")
![Ir[p-F(Me)ppy]2(dtbbpy)PF6](https://file.medchemexpress.com/product_pic/hy-w034053.gif "Click to View Ir[p-F(Me)ppy]2(dtbbpy)PF6 Product Detail")
![(Ir[dF(F)ppy]2(dCF3))PF6](https://file.medchemexpress.com/product_pic/hy-w075731.gif "Click to View (Ir[dF(F)ppy]2(dCF3))PF6 Product Detail")
![(Ir[p-Fppy]2(dtbpy))PF6](https://file.medchemexpress.com/product_pic/hy-w074187.gif "Click to View (Ir[p-Fppy]2(dtbpy))PF6 Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
iridium
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "iridium" in MCE Product Catalog:
Cat. No.: HY-160523
CAS No.: 2695594-15-9
Target:
Research Areas:
DBCO Ir catalyst is an iridium catalyst labeled with DBCO. DBCO Ir catalyst can be used for in situ labeling and imaging of biomolecules (e.g., proteins, nucleic acids) in living organisms or for constructing targeted drug delivery systems .
Cat. No.: HY-W008260
CAS No.: 12112-67-3
Synonyms: Chloro-1,5-cyclooctadiene iridium(I) dimer
Cat. No.: HY-W007596
CAS No.: 94928-86-6
Synonyms: Ir(ppy)3; Tris[2-(pyridin-2-yl)phenyl]iridium
Target:
Research Areas:
Tris(2-phenylpyridinato-C2,N)iridium(III) (Ir(ppy)3) is an iridium(III) containing organometallic complex, which is used as a phosphorescent light-emitting material. Tris(2-phenylpyridinato-C2,N)iridium(III) exhibits high luminous efficiency and good thermal stability, that can be used in organic optoelectronics, especially in improving the luminescence efficiency and stability of organic light-emitting diodes (OLEDs) .
Cat. No.: HY-W021022
CAS No.: 14996-61-3
Synonyms: iridium trichloride hydrate
Cat. No.: HY-W020887
CAS No.: 12246-51-4
Synonyms: Chlorobis(cyclooctene)iridium(I)dimer
[IrCl(COE)2]2 (Chlorobis(cyclooctene)iridium(I)dimer) is a transition metal catalyst with remarkable catalytic activity. It is widely used in catalyzing a variety of organic reactions, especially in the synthesis of unsaturated compounds. In addition, [IrCl(COE)2]2 has shown potential anti-tumor properties in biochemical research.
Cat. No.: HY-148365
Purity: 98.02%
Target:
Research Areas:
NecroIr1 is an iridium(III) complex, serves as necroptosis inducers in Cisplatin (HY-17394)-resistant lung cancer cells (A549R). NecroIr1 selectively accumulates in mitochondria, leading to oxidative stress and loss of mitochondrial membrane potential (MMP). NecroIr1 activates receptor-interacting serine-threonine kinase 3 (RIPK3) and Mixed Lineage Kinase (MLKL), and regulates CDK4 expression .
Cat. No.: HY-148366
Purity: 98.99%
Target:
Research Areas:
NecroIr2 is an iridium(III) complex, serves as necroptosis inducers in Cisplatin (HY-17394)-resistant lung cancer cells (A549R). NecroIr2 selectively accumulates in mitochondria, leading to oxidative stress and loss of mitochondrial membrane potential (MMP). NecroIr2 activates receptor-interacting serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like pseudokinase (MLKL), and regulates CDK4 expression .
Cat. No.: HY-W035155
CAS No.: 38465-86-0
(1,5-Cyclooctadiene)bis(methyldiphenylphosphine)iridium(I) hexafluorophosphate is a highly efficient catalyst with excellent hydrogenation activity. It can catalyze the reaction of hydrogen and organic substrates in various chemical reactions. This compound is often used to synthesize important chemical intermediates and compounds.
Cat. No.: HY-W034041
CAS No.: 370878-69-6
Synonyms: Tris(2-(4-fluorophenyl)pyridine)iridium; Tris[5-fluoro-2-(2-pyridinyl-kN)phenyl-kC]iridium(III)
Target:
Ir(pF-ppy)3 (Tris(2-(4-fluorophenyl)pyridine)iridium) is a compound that catalyzes photoreactions and has excellent photocatalytic activity. Ir(pF-ppy)3 can be used as a catalyst in organic reactions, especially in photocatalytic synthesis. Ir(pF-ppy)3 shows its unique advantages in promoting electron transfer and improving reaction selectivity. Ir(pF-ppy)3 is also used to improve the efficiency of displays and solar cells.
Cat. No.: HY-W009022
CAS No.: 1251-85-0
Cat. No.: HY-W035599
CAS No.: 1311386-93-2
Synonyms: Tris(2-(3-tert-butylphenyl)-4-tert-butylpyridine)iridium
Ir[pF(t-Bu)-ppy]3 (Tris(2-(3-tert-butylphenyl)-4-tert-butylpyridine)iridium) is an effective photocatalyst with excellent catalytic activity. Ir[pF(t-Bu)-ppy]3 can promote organic reactions, especially showing significant potential in the synthesis of new organic compounds. Ir[pF(t-Bu)-ppy]3 can be used to develop green chemical processes and reduce the impact of traditional catalysts on the environment. Ir[pF(t-Bu)-ppy]3 also has broad prospects in photoelectrochemical applications.
Cat. No.: HY-162820
Target:
Research Areas:
Bcl-2-IN-21 (compound C1) is an iridium compound with anticancer activity that targets and inhibits Bcl-2. Bcl-2-IN-21 inhibits colony formation of cancer cells and induces elevated levels of Bax and caspase 3 .
Cat. No.: HY-162463
CAS No.: 3033235-42-3
Target:
Research Areas:
Ir-UA is an usnic acid-derived iridium(III) complex that enhances PD-L1 expression and converts "cold tumors" into "hot tumors." Ir-UA stimulates PD-L1 expression by explicitly regulating the PD-L1 transcription factor .
Cat. No.: HY-W072530
CAS No.: 106294-60-4
Cat. No.: HY-W034053
CAS No.: 808142-88-3
Cat. No.: HY-W075731
CAS No.: 2030437-90-0
Cat. No.: HY-W074187
CAS No.: 1449110-90-0
Target:
Research Areas:
(Ir[Fppy]2(dtbpy))PF6 is an iridium-based compound that can be used as a visible light photo-redox catalyst and is applied in organic synthesis and photochemical reactions.
Cat. No.: HY-W040267
CAS No.: 92220-65-0
Target:
Research Areas:
Dichlorotetrakis(2-(2-pyridinyl)phenyl)diiridium(III) is a precursor for certain OLED Iridium compounds. Dichlorotetrakis(2-(2-pyridinyl)phenyl)diiridium(III) can be used as a catalyst. Dichlorotetrakis(2-(2-pyridinyl)phenyl)diiridium(III) can also be used in the synthesis of 3,3′-([2,2′-bipyridine]-5,5′-diylbis(methylene))bis(1-ethyl-1H-imidazol-3-ium) functionalized receptor Ir-1 .
Cat. No.: HY-182066
Target:
Research Areas:
Photosensitizer-9 is an iridium (III)-based photosensitizer with anti-melanoma activity. Photosensitizer-9 exhibits significant phototoxicity (IC50=0.98 μM) and an ideal phototoxicity index (PI=3.05). Under light irradiation, Photosensitizer-9 generates large amounts of intracellular •OH in an oxygen-independent manner. Photosensitizer-9 mediates photodynamic therapy under hypoxic conditions and synergistically activates PANoptosis (by upregulating cleaved Caspase-3, GSDMD-N, p-MLKL), ferroptosis (by disrupting the GSH-GPX4-LPO axis), apoptosis, pyroptosis and necroptosis in melanoma cells. Photosensitizer-9 induces immunogenic cell death by promoting the release of damage-associated molecular patterns under hypoxic conditions and increases the maturation rate of dendritic cells. Photosensitizer-9 reduces tumor volume in melanoma-bearing mice. Photosensitizer-9 is applicable to relevant studies on melanoma .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
