3033235-42-3
3033235-42-3
Chemical Structure
Ir-UA
- CAS No.: 3033235-42-3
- Formula:C52H43F6IrN5O6P2+
- Molecular Weight:1171.11
InChIKey: BONHCGFURMBANI-PIWPQTEHSA-N
SMILES: OC1=C(C(O)=C2C(C)(C(OC2=C1C(C)=O)=CC/3=O)C(C3=C(C)\NCC4=CC=[N](C(C5=[N]6C=CC(C)=C5)=C4)[Ir+3]786(C9=CC=CC=C9C%10=[N]8C=CC=C%10)[N]%11=CC=CC=C%11C%12=CC=CC=C%127)=O)C.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
Biological Activity: Ir-UA is an usnic acid-derived iridium(III) complex that enhances PD-L1 expression and converts "cold tumors" into "hot tumors." Ir-UA stimulates PD-L1 expression by explicitly regulating the PD-L1 transcription factor[1].
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Ir-UA | Ir-UA is an usnic acid-derived iridium(III) complex that enhances PD-L1 expression and converts "cold tumors" into "hot tumors." Ir-UA stimulates PD-L1 expression by explicitly regulating the PD-L1 transcription factor. | |||||||||||||||||||||
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