7 Results for "

ispinesib

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "ispinesib" in MCE Product Catalog:

7
Ispinesib
Ispinesib
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7 Cited Publications
Art. -Nr.: HY-50759
CAS. Nr.: 336113-53-2
Synonyms: SB-715992; CK-0238273
Target:  

Kinesin Apoptosis

Forschungsgebiete:  

Cancer

Ispinesib is a specific inhibitor of kinesin spindle protein (KSP), with a Ki app of 1.7 nM.
MC-Val-Cit-PAB-Ispinesib
MC-Val-Cit-PAB-Ispinesib
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Art. -Nr.: HY-160441
CAS. Nr.: 1629737-40-1
Target:  

Drug-Linker Conjugates for ADC Kinesin

Forschungsgebiete:  

Neurological Disease Cancer

MC-Val-Cit-PAB-Ispinesib (Compound 509) is a drug-linker conjugate for ADC, consisting of a cleavable ADC linker and Eg5 inhibitor. MC-Val-Cit-PAB-Ispinesib can be used for the synthesis of antibody-drug conjugates (ADCs) .
AZD4877
AZD4877
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Art. -Nr.: HY-13224
CAS. Nr.: 758722-49-5
Reinheit:  99.49%
Target:  

Kinesin Apoptosis Mitosis

Forschungsgebiete:  

Cancer

AZD4877 is another isostere to Ispinesib (HY-50759)and also a kinesin spindle protein (Eg5) inhibitor with IC50 of 2 nM.AZD4877 arrests cell mitosis, leads to the formation of the monopolar spindle phenotype and induces apoptosis. AZD4877 inhibits circulating peripheral blood mononuclear cells (PBMCs) and has anti-cancer activity .
Ispinesib (Standard)
Ispinesib (Standard)
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Art. -Nr.: HY-50759R
CAS. Nr.: 336113-53-2
Synonyms: SB-715992 (Standard); CK-0238273 (Standard)
Target:  

Kinesin Apoptosis Reference Standards

Forschungsgebiete:  

Cancer

Ispinesib (Standard) is the analytical standard of Ispinesib. This product is intended for research and analytical applications. Ispinesib is a specific inhibitor of kinesin spindle protein (KSP), with a Ki app of 1.7 nM.
Ispinesib-d5
Ispinesib-d5
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Art. -Nr.: HY-50759S
Synonyms: SB-715992-d5
Ispinesib-d5 (SB-715992-d5) is a deuterium labeled Ispinesib (HY-50759). Ispinesib is a specific inhibitor of kinesin spindle protein (KSP) .
Ispinesib mesylate
Ispinesib mesylate
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Art. -Nr.: HY-50759A
CAS. Nr.: 514820-03-2
Synonyms: SB-715992 mesylate; CK-0238273 mesylate
Target:  

Kinesin Apoptosis

Forschungsgebiete:  

Cancer

Ispinesib (SB-715992) mesylate is a specific inhibitor of kinesin spindle protein (KSP), with a Ki app of 1.7 nM.
F1-ispinesib
F1-ispinesib
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Art. -Nr.: HY-180188
Target:  

Autophagy

Forschungsgebiete:  

Cardiovascular Disease Cancer

F1-ispinesib is a heterobifunctional F1-autophagy degrader, composed of an RNA-binding fragment (F1) and the LC3B ligand Ispinesib (HY-50759). F1-ispinesib induces degradation of COL15A1 mRNA via an LC3B-dependent macroautophagy mechanism. F1-ispinesib inhibits cell proliferation and enhances migration of human aortic smooth muscle cells .
Assay Types