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labdane diterpenoids

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By Targets:	Bacterial (1) Biochemical Assay Reagents (1) Drug Derivative (2) Drug Intermediate (1) Endogenous Metabolite (1) Insecticide (1)
By Research Areas:	Cancer (3) Inflammation/Immunology (1) Neurological Disease (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-121839

Manoyl oxide	Endogenous Metabolite	Others
Manoyl oxide is a labdane-type diterpenoid. Manoyl oxide is the precursor of Forskolin (HY-15371) .

HY-N9017

12E,14-Labdadien-20,8β-olide	Others	Others
12E,14-Labdadien-20,8β-olide, a labdane diterpenoid, is a natural product that can be isolated from the rhizomes of Isodon yuennanensis .

HY-N8108

Sterebin E	Others	Others
Sterebin E is a labdane diterpenoid that can be found in Stevia rebaudiana leaves .

HY-N3803

trans-Communol	Others	Others
trans-Communol is a labdane diterpenoid, can be isolated from the aerial parts of Salvia cinnabarina .

HY-N1488

14-Deoxy-17-hydroxyandrographolide 14-Deoxy-17β-hydroxyandrographolide	Drug Derivative	Others
14-Deoxy-17-hydroxyandrographolide is an ent-labdane diterpenoid compound isolated from the aerial parts of Andrographis paniculate .

HY-N2867

Andrographiside	Bacterial	Cancer
Andrographiside is a labdane diterpenoid glucoside that can be isolated from the leaves of Andrographis paniculata Nees. Andrographiside has antihepatotoxic and antioxidative effects. Andrographiside shows protective effects on mice with hepatotoxicity induced by carbon tetrachloride or tert-butylhydroperoxide (tBHP) . Andrographiside is a novel biofilm inhibitor of Pseudomonas aeruginosa PAO1 by modulating quorum-sensing proteins .

HY-N17484

Agatholic acid	Others	Others
Agatholic acid is a labdane-type diterpenoid acid that can be found in defoliated twigs of Pinus pumila .

HY-136974

9-Deoxyforskolin	Drug Derivative	Others
9-Deoxyforskolin (compound 2) is a labdane-type diterpenoid, and also a forskolin derivative identified in hairy root cultures of Coleus forskohlii .

HY-N16811

Yunnancoronarin C	Others	Cancer
Yunnancoronarin C is a labdane-type diterpenoid that can be isolated from the rhizomes of Hedychium forrestii, exhibits cytotoxicity against leukemia cells. Yunnancoronarin C can be used for the research of leukemia .

HY-N17787

Labdanolic acid	Drug Intermediate	Inflammation/Immunology
Labdanolic acid is a labdane-type diterpenoid compound that can be isolated from Cistus ladaniferus, a plant growing in Portugal. Labdanolic acid is a key intermediate in the synthesis of anti-inflammatory molecules and has both medicinal and industrial applications .

HY-N1384B

(rel)-Ambroxide	Biochemical Assay Reagents	Others
(rel)-Ambroxide is the racemic form of Ambroxide (HY-N1384). Ambroxide is a naturally occurring terpenoid. Ambroxide is one of the key constituents of ambergris. Ambroxide is used in the manufacture of high-end perfumes to improve the aroma quality and fragrance lasting time of perfumes .

HY-N15634

Anticopalic acid	Insecticide	Neurological Disease
Anticopalic acid is a labdane-type diterpenoid insect antifeedant that exhibits dose-dependent antifeedant activity against the fall armyworm (Spodoptera frugiperda). Anticopalic acid can be isolated from Vitex hemsleyi. Anticopalic acid may be involved in neuroreceptor-mediated insect taste regulation and could be used to develop environmentally friendly antifeedants targeting lepidopteran pests .

HY-N19664

14-Deoxy-12-methoxyandrographolide	Others	Cancer
14-Deoxy-12-methoxyandrographolide, an ent-labdane-type diterpenoid found in the aerial parts of Andrographis paniculata, is a cell differentiation inducer. 14-Deoxy-12-methoxyandrographolide induces differentiation of myeloid leukemia cells via increased phagocytosis of polystyrene latex particles. 14-Deoxy-12-methoxyandrographolide can be used for the research of myeloid leukemia .

12E,14-Labdadien-20,8β-olide	Other Terpenoids Classification of Application Fields Terpenoids Labiatae Carpesium cernuum L. Other Diseases Plants Disease Research Fields Source Classification	Others
12E,14-Labdadien-20,8β-olide, a labdane diterpenoid, is a natural product that can be isolated from the rhizomes of Isodon yuennanensis .

Sterebin E	Trifolium hybridum L. Classification of Application Fields Terpenoids Other Diseases Diterpenoids Plants Compositae Disease Research Fields Source Classification	Others
Sterebin E is a labdane diterpenoid that can be found in Stevia rebaudiana leaves .

trans-Communol	Periandra mediterranea (Vell.) Taub. Terpenoids Labiatae Diterpenoids Plants Source Classification	Others
trans-Communol is a labdane diterpenoid, can be isolated from the aerial parts of Salvia cinnabarina .

Andrographiside	Structural Classification Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Source Classification	Bacterial
Andrographiside is a labdane diterpenoid glucoside that can be isolated from the leaves of Andrographis paniculata Nees. Andrographiside has antihepatotoxic and antioxidative effects. Andrographiside shows protective effects on mice with hepatotoxicity induced by carbon tetrachloride or tert-butylhydroperoxide (tBHP) . Andrographiside is a novel biofilm inhibitor of Pseudomonas aeruginosa PAO1 by modulating quorum-sensing proteins .

Agatholic acid	Structural Classification Pinaceae Terpenoids Pinus pumila (Pall.) Regel Diterpenoids Plants Source Classification	Others
Agatholic acid is a labdane-type diterpenoid acid that can be found in defoliated twigs of Pinus pumila .

9-Deoxyforskolin	Structural Classification Terpenoids Labiatae Diterpenoids Plants Pueraria montana (Lour.) Merr. Source Classification	Drug Derivative
9-Deoxyforskolin (compound 2) is a labdane-type diterpenoid, and also a forskolin derivative identified in hairy root cultures of Coleus forskohlii .

Yunnancoronarin C	Structural Classification Hedychium forrestii Diels Terpenoids Diterpenoids Plants Source Classification Zingiberaceae	Others
Yunnancoronarin C is a labdane-type diterpenoid that can be isolated from the rhizomes of Hedychium forrestii, exhibits cytotoxicity against leukemia cells. Yunnancoronarin C can be used for the research of leukemia .

Labdanolic acid	Structural Classification Ketones, Aldehydes, Acids Talinum calycinum Engelm. in Wisl. Plants Talinaceae Source Classification	Drug Intermediate
Labdanolic acid is a labdane-type diterpenoid compound that can be isolated from Cistus ladaniferus, a plant growing in Portugal. Labdanolic acid is a key intermediate in the synthesis of anti-inflammatory molecules and has both medicinal and industrial applications .

(rel)-Ambroxide	Other Terpenoids Structural Classification other families Animals Terpenoids Plants Source Classification	Biochemical Assay Reagents
(rel)-Ambroxide is the racemic form of Ambroxide (HY-N1384). Ambroxide is a naturally occurring terpenoid. Ambroxide is one of the key constituents of ambergris. Ambroxide is used in the manufacture of high-end perfumes to improve the aroma quality and fragrance lasting time of perfumes .

Anticopalic acid	Structural Classification Ketones, Aldehydes, Acids Labiatae Petasites hybridus (L.) G.Gaertn., B.Mey. & Schreb. Plants Source Classification	Insecticide
Anticopalic acid is a labdane-type diterpenoid insect antifeedant that exhibits dose-dependent antifeedant activity against the fall armyworm (Spodoptera frugiperda). Anticopalic acid can be isolated from Vitex hemsleyi. Anticopalic acid may be involved in neuroreceptor-mediated insect taste regulation and could be used to develop environmentally friendly antifeedants targeting lepidopteran pests .

14-Deoxy-12-methoxyandrographolide	Structural Classification Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Source Classification	Others
14-Deoxy-12-methoxyandrographolide, an ent-labdane-type diterpenoid found in the aerial parts of Andrographis paniculata, is a cell differentiation inducer. 14-Deoxy-12-methoxyandrographolide induces differentiation of myeloid leukemia cells via increased phagocytosis of polystyrene latex particles. 14-Deoxy-12-methoxyandrographolide can be used for the research of myeloid leukemia .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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labdane diterpenoids

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