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Results for "

metamorphosis

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

Peptides

6

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6979
    Crustecdysone
    10+ Cited Publications

    20-Hydroxyecdysone

    		 Caspase Autophagy Endogenous Metabolite Cardiovascular Disease
    Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .
    Crustecdysone
  • HY-W017113
    2-Mercaptobenzothiazole
    1 Publications Verification

    		 Environmental Pollutants Endogenous Metabolite Metabolic Disease
    2-Mercaptobenzothiazole is an activator of the aryl hydrocarbon receptor (AhR) , inhibiting thyroid hormone synthesis and dopamine beta-hydroxylase activity . 2-Mercaptobenzothiazole promotes bladder cancer cell invasion by altering the conformation of the AhR ligand binding domain (LBD), activating AhR transcription, and upregulating the mRNA and protein expression of target genes CYP1A1 and CYP1B1 . 2-Mercaptobenzothiazole inhibits thyroid peroxidase (TPO) with an IC50 value of 11.5 μM, induces histological changes such as follicular cell hypertrophy in Xenopus laevis tadpoles, delaying metamorphosis . 2-Mercaptobenzothiazole increases chromosomal aberrations and sister chromatid exchanges (SCEs) in Chinese hamster ovary (CHO) cells, and enhances carcinogenicity in F344/N rats . 2-Mercaptobenzothiazole inhibits norepinephrine synthesis in mice and completely blocks the conversion of exogenous dopamine to norepinephrine in rat cardiomyocytes .
    2-Mercaptobenzothiazole
  • HY-A0152
    D-Thyroxine

    D-T4

    		 Endogenous Metabolite Metabolic Disease
    D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. D-Thyroxine can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia .
    D-Thyroxine
  • HY-W020772
    Aminoguanidine hemisulfate
    5+ Cited Publications

    		 Reactive Oxygen Species (ROS) Cancer
    Aminoguanidine hemisulfate is an inhibitor of NOS and ROS. Aminoguanidine hemisulfate abolishes ANE-induced ROS production in vitro. Aminoguanidine hemisulfate is used for cancer research .
    Aminoguanidine hemisulfate
  • HY-W339331
    Flubendiamide

    NNI-0001

    		 Insecticide Calcium Channel Reactive Oxygen Species (ROS) Apoptosis Infection Metabolic Disease
    Flubendiamide (NNI-0001) is an orally active phthalic diamide insecticide that acts by targeting insect ryanodine receptors (RyRs), causing insect muscle dysfunction, paralysis and death. Flubendiamide disrupts molting, metamorphosis and reproductive processes, induces oxidative stress by increasing the levels of ROS/RNS, MDA and 8OHdG and decreasing the levels of SOD, CAT and GST, activates the CncC/Maf apoptosis pathway, impairs calcium homeostasis, promotes adipogenesis, increases triglyceride accumulation, and upregulates the expression of regulatory factors for adipocyte differentiation and adipogenesis .
    Flubendiamide
  • HY-N12864
    Isocyasterone

    		Others Others
    Isocyasterone is an insect metamorphosing substance, which can be isolated from Cyathula capitata .
    Isocyasterone
  • HY-177745
    25-Azacoprostane

    5β-Cholan-24-dimethylamine

    		 Insecticide Infection
    25-Azacoprostane (5β-Cholan-24-dimethylamine) is an azasteroid. 25-Azacoprostane has significant inhibitory activity against the molting and metamorphosis processes of various insects. 25-Azacoprostane can be used as insecticide .
    25-Azacoprostane
  • HY-W011786
    2-Chloro-1-(4-fluorobenzyl)-1H-benzo[d]imidazole

    		Aldose Reductase Metabolic Disease
    2-Chloro-1-(4-fluorobenzyl)-1H-benzo[d]imidazole is an inhibitor of larval settlement in marine organisms, demonstrating low toxicity while effectively inhibiting the metamorphosis of species such as barnacles, bryozoans, and polychaetes. 2-Chloro-1-(4-fluorobenzyl)-1H-benzo[d]imidazole also exhibits activity as an aldose reductase (ALR2) inhibitor, indicating potential therapeutic applications in diabetes-related complications.
    2-Chloro-1-(4-fluorobenzyl)-1H-benzo[d]imidazole
  • HY-N6979R
    Crustecdysone (Standard)

    20-Hydroxyecdysone (Standard)

    		 Reference Standards Caspase Autophagy Endogenous Metabolite Cardiovascular Disease
    Crustecdysone (Standard) is the analytical standard of Crustecdysone. This product is intended for research and analytical applications. Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .
    Crustecdysone (Standard)
  • HY-A0152A
    D-Thyroxine sodium

    D-T4 sodium

    		 Thyroid Hormone Receptor Cardiovascular Disease
    D-thyroxine (D-T4) sodium is an orally active thyroid hormone that inhibits the secretion of TSH. D-thyroxine sodium can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-thyroxine sodium can be used for the study of hypercholesterolemia .
    D-Thyroxine sodium
  • HY-A0152R
    D-Thyroxine (Standard)

    D-T4 (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    D-Thyroxine (Standard) is the analytical standard of D-Thyroxine (HY-A0152). This product is intended for research and analytical applications. D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. D-Thyroxine can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia .
    D-Thyroxine (Standard)
  • HY-W033687
    Triclopyr triethylamine

    		Herbicide Others
    Triclopyr triethylamine is a herbicide. Triclopyr triethylamine causes lethargy in metamorphic northern red-legged frogs during exposure, and delays the completion time of metamorphosis in northern red-legged frogs. Triclopyr triethylamine is used to control broadleaf emergent aquatic weeds, such as the invasive species Lythrum salicaria .
    Triclopyr triethylamine

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