137-53-1
137-53-1
Chemical Structure
D-Thyroxine sodium
Synonym(s): D-T4 sodium
- CAS. Nr.: 137-53-1
- Formula:C15H10I4NNaO4
- Molecular Weight:798.85
IUPAC Name: sodium (R)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate
InChIKey: YDTFRJLNMPSCFM-UTONKHPSSA-M
SMILES: N[C@H](CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(O)C(I)=C2)C(O[Na])=O
Biological Activity: D-thyroxine (D-T4) sodium is an orally active thyroid hormone that inhibits the secretion of TSH. D-thyroxine sodium can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-thyroxine sodium can be used for the study of hypercholesterolemia[1][2][3].
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D-Thyroxine sodium | D-thyroxine (D-T4) sodium is an orally active thyroid hormone that inhibits the secretion of TSH. D-thyroxine sodium can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-thyroxine sodium can be used for the study of hypercholesterolemia. | |||||||||||||||||||||
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References
- [1]. John J. Schrogie M.D., et al. II. The effect of D-thyroxine, clofibrate, and norethandrolone. Clinical Pharmacology and Therapeutics, Volume8, Issue1part1 January 1967 Pages 70-77
- [2]. Raluca-IoanaStefan, et al. Simultaneous determination of l-thyroxine (l-T4), d-thyroxine (d-T4), and l-triiodothyronine (l-T3) using a sensors/sequential injection analysis system.
- [3]. TUCKER RG. The biologic effects of D-thyroxine. A review. Angiology. 1962 Feb;13:85-8. [Content Brief]
