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10 Results for "
monohydroxy fatty acids
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "monohydroxy fatty acids" in MCE Product Catalog:
Synonyms: (±)-13-HODE
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(±)13-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. It is the principle hydroxylated fatty acid in human psoriatic skin scales, with a mean concentration of 17 ng/mg.
Cat. No.: HY-113943A
CAS No.: 70968-92-2
Synonyms: (±)9-HETE
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9-HETE, a monohydroxy fatty acid, is the lipoxygenase metabolite of arachidonic acid (HY-109590) .
Cat. No.: HY-121987A
CAS No.: 77159-57-0
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(±)15-HEDE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE. 15-HEDE is formed from eicosadienoic acid in macrophages. It inhibits 5-lipoxygenase (5-LO; IC50=35 μM).
Cat. No.: HY-W552832
CAS No.: 4158-12-7
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Cat. No.: HY-W747548
CAS No.: 116180-17-7
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12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.
Cat. No.: HY-130675
CAS No.: 88852-33-9
Synonyms: (±)15-hydroxyeicosapentaenoic acid; 15-OHEPA
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(±)15-HEPE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEPE and 15(S)-HEPE (HY-130675A). (±)15-HEPE is active against P. acnes and S. aureus (MICs = 128 and 512 mg/L, respectively). It inhibits aggregation of isolated rat neutrophils induced by the formyl peptide receptor agonist fMLP (IC50 = 4.7 µM). Bronchoalveolar lavage fluid (BALF) levels of (±)15-HEPE are increased in patients with allergic asthma or COVID-19.
Cat. No.: HY-112653A
CAS No.: 70968-93-3
Synonyms: 8-Hydroxy-5(Z),9(E),11(Z),14(Z)-eicosatetraenoic acid
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Cat. No.: HY-130310B
CAS No.: 5598-37-8
Synonyms: 11-hydroxy-12,14-Eicosadienoic acid
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(±)11-HEDE is a racemic mixture of the monohydroxy fatty acids 11(S)-HEDE and 11(R)-HEDE. 11-HEDE is formed from eicosadienoic acid by cyclooxygenase (COX) and in macrophages.
Cat. No.: HY-113943
CAS No.: 107656-13-3
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9(S)-HETE is the S isomer of 9-HETE (HY-113943A). 9-HETE, a monohydroxy fatty acid, is the lipoxygenase metabolite of arachidonic acid (HY-109590) .
Cat. No.: HY-113281
CAS No.: 44843-89-2
Target:
fatty acids with medium chain lengths (particularly hexanoic acid). 5-Hydroxyhexanoic acid functions as a predictor of early renal functional decline in type 2 diabetes with microalbuminuria .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
