2. Metabolic Enzyme/Protease
  3. Lipoxygenase
  4. (±)15-HEDE

(±)15-HEDE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE. 15-HEDE is formed from eicosadienoic acid in macrophages. It inhibits 5-lipoxygenase (5-LO; IC50=35 μM).

For research use only. We do not sell to patients.

(±)15-HEDE

(±)15-HEDE Chemical Structure

CAS No. : 77159-57-0

Size Price Stock
Solvent
25 μg (308.17 μM * 250 μL in Ethanol) Ask For Quote & Lead Time
Solvent
50 μg (308.17 μM * 500 μL in Ethanol) Ask For Quote & Lead Time
Solvent
100 μg (308.17 μM * 1 mL in Ethanol) Ask For Quote & Lead Time

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Other Forms of (±)15-HEDE:

(±)15-HEDE Related Antibodies

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Description

(±)15-HEDE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE. 15-HEDE is formed from eicosadienoic acid in macrophages. It inhibits 5-lipoxygenase (5-LO; IC50=35 μM).

Cellular Effect
Cell Line Type Value Description References
RBL-1 IC50
35 μM
Compound: 16
Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase
Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase
[PMID: 3806609]
Molecular Weight

324.50

Formula

C20H36O3
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CCCCCC(O)/C=C/C=C\CCCCCCCCCC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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(±)15-HEDE Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(±)15-HEDE77159-57-0LipoxygenaseLOXInhibitorinhibitorinhibit

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