(±)15-HEDE
(±)15-HEDE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE. 15-HEDE is formed from eicosadienoic acid in macrophages. It inhibits 5-lipoxygenase (5-LO; IC50=35 μM).
For research use only. We do not sell to patients.
- CAS No.: 77159-57-0
- Formula: C20H36O3
- Molecular Weight:324.50
-
Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
35 μM
Compound: 16
|
Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase
Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase
|
[PMID: 3806609] |
Chemical Information
-
CAS No. 77159-57-0
-
Appearance Liquid
-
Molecular Weight 324.50
-
Formula C20H36O3
-
Color Colorless to light yellow
-
SMILES
CCCCCC(O)/C=C/C=C\CCCCCCCCCC(O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
-
Data Sheet (261 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)