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Cat. No.: HY-121987A

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(±)15-HEDE

(±)15-HEDE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE. 15-HEDE is formed from eicosadienoic acid in macrophages. It inhibits 5-lipoxygenase (5-LO; IC₅₀=35 μM).

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CAS No.: 77159-57-0
Formule: C₂₀H₃₆O₃
Masse moléculaire:324.50

Stockage:

Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

(±)15-HEDE Chemical Structure

CAS No.: 77159-57-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Cellular Effect
Chemical Information
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Description

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Cellular Effect

Cell Line	Type	Value	Description	References
RBL-1	IC₅₀	35 μM Compound: 16	Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase	[PMID: 3806609]

Chemical Information

CAS No. 77159-57-0
Appearance Liquid
Masse moléculaire 324.50
Formule C₂₀H₃₆O₃
Color Colorless to light yellow
SMILES

CCCCCC(O)/C=C/C=C\CCCCCCCCCC(O)=O
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (261 KB)
SDS (393 KB)
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COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Haviv, et al. Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues. J. Med. Chem. 30(2), 254-263 (1987).

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(±)15-HEDE

17(R)-HDHA

trans-EKODE-(E)-Ib

1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe

(±)8(9)-EpETE

(±)14,15-Epoxyeicosatrienoic acid

8,9-DiHETE

5,6-DiHETE

15-KETE

15(S)-HPETE

15(S)-HEPE

5(S)-HETE

12(S)-HETE

Voir tous les produits spécifiques à Isoform Lipoxygenase

Activité biologique

Chemical Information

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(±)15-HEDE

17(R)-HDHA

trans-EKODE-(E)-Ib

1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe

(±)8(9)-EpETE

(±)14,15-Epoxyeicosatrienoic acid

8,9-DiHETE

5,6-DiHETE

15-KETE

15(S)-HPETE

15(S)-HEPE

5(S)-HETE

12(S)-HETE

Voir tous les produits spécifiques à Isoform Lipoxygenase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

(±)15-HEDE Related Classifications

HY-121987A Related Classifications

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