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Cat. No.: HY-121987

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15(S)-HEDE

15(S)-HEDE (Compound 8) is an analogue of 15-HEDE (HY-121987A) that inhibits 5-lipoxygenase with an IC₅₀ value of 26 μM. 15(S)-HEDE is promising for research of inflammatory disease.

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CAS No.: 92693-04-4
화학식: C₂₀H₃₆O₃
분자량:324.50

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (260 KB)

15(S)-HEDE Chemical Structure

CAS No.: 92693-04-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- Cellular Effect
Chemical Information
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Bioz

Biological Activity

제품 설명

15(S)-HEDE (Compound 8) is an analogue of 15-HEDE (HY-121987A) that inhibits 5-lipoxygenase with an IC₅₀ value of 26 μM. 15(S)-HEDE is promising for research of inflammatory disease^[1].

All Lipoxygenase Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
RBL-1	IC₅₀	26 μM Compound: 8	Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase	[PMID: 3806609]

Chemical Information

CAS No. 92693-04-4
분자량 324.50
화학식 C₂₀H₃₆O₃
SMILES

OC(CCCCCCCCC/C=C\C=C\[C@@H](O)CCCCC)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (260 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Haviv F, et al. Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues. J Med Chem. 1987 Feb;30(2):254-63. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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15(S)-HEDE

All Lipoxygenase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

15(S)-HEDE Related Classifications

HY-121987 Related Classifications