Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
ocular hypotensive
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "ocular hypotensive" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-B0584
CAS No.: 157283-68-6
Synonyms: Fluprostenol isopropyl ester; AL6221; Flu-Ipr
Target:
Research Areas:
Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
Synonyms: QLS-101
Target:
Research Areas:
Foslevcromakalim (QLS-101) is a ATP-sensitive potassium channel opener. Foslevcromakalim is the proagent used for ocular hypotensive effect .
Target:
Research Areas:
Medifoxamine is an orally active monoamine reuptake inhibitor and antidepressant. Medifoxamine preferentially inhibits presynaptic dopamine reuptake. Medifoxamine acts as an intraocular pressure-lowering agent to reduce intraocular pressure, and also functions as a miotic agent to decrease pupil diameter. Medifoxamine exhibits characteristic properties of antidepressant compounds, including preventing hypothermia induced by Reserpine (HY-N0480) or Apomorphine (HY-12723), potentiating the toxic effects of Yohimbine (HY-N0127) in mice, and reducing immobility behavior in mice and rats in the "behavioral despair" model. Medifoxamine has no anticholinergic activity. Medifoxamine can be used in research related to depression .
Target:
Research Areas:
AL-34662 is a selective 5-HT2A receptoragonist (IC50: 0.77 nM and 1.5 nM for rat and human 5-HT2 receptor). AL-34662 is also a weak α-1D adrenergic agonist activity (EC50:0.4 μM). AL-34662 is an ocular hypotensive agent .
Cat. No.: HY-130395
CAS No.: 135646-98-9
Target:
Research Areas:
15-Keto latanoprost is a metabolite of Latanoprost, which is an ocular hypotensive agent .
Cat. No.: HY-132277
CAS No.: 1163135-96-3
Target:
Research Areas:
15-Keto Bimatoprost is a prostaglandin F2α (PGF2α) analog that can be used for the research of ocular hypotensive .
Cat. No.: HY-B0584R
CAS No.: 157283-68-6
Synonyms: Fluprostenol isopropyl ester(Standard); AL6221(Standard); Flu-Ipr (Standard)
Research Areas:
Travoprost (Standard) is the analytical standard of Travoprost. This product is intended for research and analytical applications. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
Target:
Research Areas:
Bunazosin is a potent and selective α1-adrenoceptor antagonist. Bunazosin can be used for antihypertensive and ocular hypotensive research .
Cat. No.: HY-107326A
CAS No.: 52712-76-2
Target:
Research Areas:
Bunazosin hydrochloride is a potent and selective α1-adrenoceptor antagonist. Bunazosin hydrochloride can be used for antihypertensive and ocular hypotensive research .
Cat. No.: HY-119063
CAS No.: 86394-94-7
Target:
Research Areas:
L-645151 is a carbonic anhydrase inhibitor with ocular penetration and hypotensive activity. L-645151 lowers the elevated intraocular pressure (IOP) of o-chymotripsinized (o-CT) rabbit eyes. L-645151 is promising for research of an ocular hypotensive agent .
Cat. No.: HY-163994
CAS No.: 57576-17-7
Synonyms: KWD 2058 hydrochloride
Target:
Research Areas:
Ibuterol (KWD 2058) hydrochloride, a diester of Terbutaline (HY-B0802A), is an orally active, selective and effective β-stimulating agent with lipophilic activities. Ibuterol hydrochloride is also an orally active ocular hypotensive agent. Ibuterol hydrochloride relieves bronchial obstruction in asthma without causing circulatory effects. Ibuterol hydrochloride is proming for rasearch of intraocular hypertension, asthma and bronchitis .
Cat. No.: HY-B0584S2
Synonyms: Fluprostenol isopropyl ester-7; AL6221-7; Flu-Ipr-7
Cat. No.: HY-B0584A
CAS No.: 1563176-59-9
Synonyms: 5,6-trans-Fluprostenol isopropyl ester; 5,6-trans-AL6221; 5,6-trans-Flu-Ipr
Target:
Research Areas:
5,6-trans-Travoprost is the isomer of Travoprost (HY-B0584), and can be used as an experimental control. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
Cat. No.: HY-125375
CAS No.: 119731-75-8
Target:
Research Areas:
L-662583 is a locally active carbonic anhydrase II inhibitor with an IC50 value of 0.7 nM .
Cat. No.: HY-118648
CAS No.: 33854-16-9
Synonyms: PGF2α methyl ester; Dinoprost methyl
Target:
Research Areas:
Prostaglandin F2α methyl ester (PGF2α methyl ester; Dinoprost methyl) is a PGF2α analog with more lipid solubility. Prostaglandin F2α methyl ester exhibits efficacy in maintaining the ocular hypotensive .
Cat. No.: HY-132277S
Purity: 96.65%
Cat. No.: HY-114385
CAS No.: 2557327-99-6
Synonyms: 13,14-epoxy Fluprostenol isopropyl ester
Target:
Research Areas:
13,14-epoxy Travoprost (13,14-epoxy Fluprostenol isopropyl ester) is a mixture of diastereomeric epoxides generated during production of Travoprost (HY-B0584). Travoprost is a selective agonist for prostaglandin F receptor, which exhibits an ocular hypotensive efficacy .
Cat. No.: HY-176011
Synonyms: 17-Phenyl trinor PGF2α glycinamide methyl ester
Target:
Research Areas:
17-Phenyl trinor prostaglandin F2α glycinamide methyl ester is a derivative of Bimatoprost (HY-B0191) and a prostaglandin analog. 17-Phenyl trinor prostaglandin F2α glycinamide methyl ester is a human prostaglandin FP receptor agonist. 17-Phenyl trinor prostaglandin F2α glycinamide methyl ester has an ocular hypotensive effect and can be used in the study of ocular hypertension and glaucoma .
Cat. No.: HY-129934
CAS No.: 607351-44-0
Synonyms: Lat-NEt
Target:
Research Areas:
Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity.1 Prostaglandin N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that prostaglandin ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. Lat-NEt would be expected to show the typical intraocular effects of Latanoprost free acid, but with the much slower hydrolysis pharmacokinetics of the prostaglandin N-amides.
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
