57576-17-7
Chemical Structure
Ibuterol hydrochloride
Synonym(s): KWD 2058 hydrochloride
- CAS No.: 57576-17-7
- Formula:C20H32ClNO5
- Molecular Weight:401.92
InChIKey: HZCSPXISTZABFN-UHFFFAOYSA-N
SMILES: O=C(C(C)C)OC1=CC(C(CNC(C)(C)C)O)=CC(OC(C(C)C)=O)=C1.Cl
Biological Activity: Ibuterol (KWD 2058) hydrochloride, a diester of Terbutaline (HY-B0802A), is an orally active, selective and effective β-stimulating agent with lipophilic activities. Ibuterol hydrochloride is also an orally active ocular hypotensive agent. Ibuterol hydrochloride relieves bronchial obstruction in asthma without causing circulatory effects. Ibuterol hydrochloride is proming for rasearch of intraocular hypertension, asthma and bronchitis[1][2][3].
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Ibuterol hydrochloride | Ibuterol (KWD 2058) hydrochloride, a diester of Terbutaline (HY-B0802A), is an orally active, selective and effective β-stimulating agent with lipophilic activities. Ibuterol hydrochloride is also an orally active ocular hypotensive agent. Ibuterol hydrochloride relieves bronchial obstruction in asthma without causing circulatory effects. Ibuterol hydrochloride is proming for rasearch of intraocular hypertension, asthma and bronchitis. | |||||||||||||||||||||
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- [1]. Arner B, et al. Comparison between ibuterol hydrochloride and terbutaline in asthma. Br Med J. 1976 Jan 10;1(6001):72-4. [Content Brief]
- [2]. Phipps TL, et al. Effects of ibuterol, a beta-2 adrenergic prodrug, on intraocular pressure. J Ocul Pharmacol. 1986 Summer;2(3):225-37. [Content Brief]
- [3]. Larsson S, et al. Comparison of intravenous ibuterol (KWD 2058), a new bronchodilator, and terbutaline. Eur J Clin Pharmacol. 1977 Jul 19;11(6):429-33. [Content Brief]
Keywords
