15-Keto Bimatoprost-d5
Based on 1 Customer Validation
15-Keto Bimatoprost-d5 is the deuterium labeled 15-Keto Bimatoprost. 15-Keto Bimatoprost is a prostaglandin F2α (PGF2α) analog that can be used for the research of ocular hypotensive.
For research use only. We do not sell to patients.
- Purity: 96.65%
- Formula: C25H30D5NO4
- Molecular Weight:418.58
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 1163135-96-3
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Appearance Solid
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Molecular Weight 418.58
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Formula C25H30D5NO4
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Color Off-white to light yellow
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SMILES
O=C(NC([2H])([2H])C([2H])([2H])[2H])CCC/C=C\C[C@@H]1[C@@H](/C=C/C(CCC2=CC=CC=C2)=O)[C@H](O)C[C@@H]1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
Ethanol : ≥ 10 mg/mL (23.89 mM)
DMF : ≥ 2.5 mg/mL (5.97 mM)
DMSO : ≥ 2 mg/mL (4.78 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Rahman MS, et al. Screening and quantification of undeclared PGF2α analogs in eyelash-enhancing cosmetic serums using LC-MS/MS. J Pharm Biomed Anal. 2022 Sep 20;219:114940. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / DMF / Ethanol | 1 mM | 2.3890 mL | 11.9451 mL | 23.8903 mL | 59.7257 mL |
| DMF / Ethanol | 5 mM | 0.4778 mL | 2.3890 mL | 4.7781 mL | 11.9451 mL |
| Ethanol | 10 mM | 0.2389 mL | 1.1945 mL | 2.3890 mL | 5.9726 mL |
| 15 mM | 0.1593 mL | 0.7963 mL | 1.5927 mL | 3.9817 mL | |
| 20 mM | 0.1195 mL | 0.5973 mL | 1.1945 mL | 2.9863 mL |
15-Keto Bimatoprost-d5 Related Classifications
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